التفاصيل البيبلوغرافية
العنوان: |
Molecular remission of Philadelphia/bcr‐abl‐positive acute myeloid leukaemia after treatment with anti‐CD33 calicheamicin conjugate (gemtuzumab ozogamicin, CMA‐676) |
المؤلفون: |
De Vetten, M. P., Jansen, J. H., Van Der Reijden, B. A., Berger, M. S., Zijlmans, J. M. J. M., Löwenberg, B. |
المصدر: |
British Journal of Haematology ; volume 111, issue 1, page 277-279 ; ISSN 0007-1048 1365-2141 |
بيانات النشر: |
Wiley |
سنة النشر: |
2000 |
المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
الوصف: |
The anti‐CD33 monoclonal antibody linked to NAc‐gamma calicheamicin gemtuzumab ozogamicin (CMA‐676) was used to treat a patient with Philadelphia/bcr‐abl‐positive acute myeloid leukaemia. We report a morphological and cytogenetic complete remission after treatment with two doses of gemtuzumab ozogamicin as a single agent. Using real‐time polymerase chain reaction (PCR), gemtuzumab ozogamicin treatment resulted in a 3‐log tumour mass reduction in bone marrow. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1111/j.1365-2141.2000.02402.x |
الإتاحة: |
https://doi.org/10.1111/j.1365-2141.2000.02402.xTest |
حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
رقم الانضمام: |
edsbas.E10DA573 |
قاعدة البيانات: |
BASE |