التفاصيل البيبلوغرافية
| العنوان: |
Species-specific effects of the introduction of Aspergillus nidulans gfdB in osmophilic aspergilli |
| المؤلفون: |
Bodnár, Veronika, Király, Anita, Orosz, Erzsébet, Miskei, Márton, Emri, Tamás, Karányi, Zsolt, Leiter, Éva, de Vries, Ronald P., Pócsi, István |
| المساهمون: |
University of Debrecen |
| المصدر: |
Applied Microbiology and Biotechnology ; volume 107, issue 7-8, page 2423-2436 ; ISSN 0175-7598 1432-0614 |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Applied Microbiology and Biotechnology, General Medicine, Biotechnology |
| الوصف: |
Industrial fungi need a strong environmental stress tolerance to ensure acceptable efficiency and yields. Previous studies shed light on the important role that Aspergillus nidulans gfdB , putatively encoding a NAD + -dependent glycerol-3-phosphate dehydrogenase, plays in the oxidative and cell wall integrity stress tolerance of this filamentous fungus model organism. The insertion of A. nidulans gfdB into the genome of Aspergillus glaucus strengthened the environmental stress tolerance of this xerophilic/osmophilic fungus, which may facilitate the involvement of this fungus in various industrial and environmental biotechnological processes. On the other hand, the transfer of A. nidulans gfdB to Aspergillus wentii , another promising industrial xerophilic/osmophilic fungus, resulted only in minor and sporadic improvement in environmental stress tolerance and meanwhile partially reversed osmophily. Because A. glaucus and A. wentii are phylogenetically closely related species and both fungi lack a gfdB ortholog, these results warn us that any disturbance of the stress response system of the aspergilli may elicit rather complex and even unforeseeable, species-specific physiological changes. This should be taken into consideration in any future targeted industrial strain development projects aiming at the fortification of the general stress tolerance of these fungi. Key points • A. wentii c’ gfdB strains showed minor and sporadic stress tolerance phenotypes. • The osmophily of A. wentii significantly decreased in the c’ gfdB strains. • Insertion of gfdB caused species-specific phenotypes in A. wentii and A. glaucus. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1007/s00253-023-12384-9 |
| DOI: |
10.1007/s00253-023-12384-9.pdf |
| DOI: |
10.1007/s00253-023-12384-9/fulltext.html |
| الإتاحة: |
https://doi.org/10.1007/s00253-023-12384-9Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.DD31550A |
| قاعدة البيانات: |
BASE |
