دورية أكاديمية
A research agenda on the management of intra-abdominal candidiasis: Results from a consensus of multinational experts
| العنوان: | A research agenda on the management of intra-abdominal candidiasis: Results from a consensus of multinational experts |
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| المؤلفون: | Bassetti, Matteo, Marchetti, Monia, Chakrabarti, Arunaloke, Colizza, Sergio, Garnacho Montero, Jose, Kett, Daniel H., Munoz, Patricia, Cristini, Francesco, Andoniadou, Anastasia, Viale, Pierluigi, Rocca, Giorgio Della, Roilides, Emmanuel, Sganga, Gabriele, Walsh, Thomas J., Tascini, Carlo, Tumbarello, Mario, Righi, Elda, Eckmann, Christian, Viscoli, Claudio, Shorr, Andrew F., Leroy, Olivier, Petrikos, George, De Rosa, Francesco Giuseppe, MENICHETTI, FRANCESCO |
| المساهمون: | Bassetti, Matteo, Marchetti, Monia, Chakrabarti, Arunaloke, Colizza, Sergio, Garnacho Montero, Jose, Kett, Daniel H., Munoz, Patricia, Cristini, Francesco, Andoniadou, Anastasia, Viale, Pierluigi, Rocca, Giorgio Della, Roilides, Emmanuel, Sganga, Gabriele, Walsh, Thomas J., Tascini, Carlo, Tumbarello, Mario, Menichetti, Francesco, Righi, Elda, Eckmann, Christian, Viscoli, Claudio, Shorr, Andrew F., Leroy, Olivier, Petrikos, George, De Rosa, Francesco Giuseppe |
| سنة النشر: | 2013 |
| المجموعة: | ARPI - Archivio della Ricerca dell'Università di Pisa |
| مصطلحات موضوعية: | Abdominal infection, Candida, Consensu, Abdominal Absce, Adult, Antifungal Agent, Bacteriological Technique, Candidiasi, DNA, Fungal, Human, Intraabdominal Infection, Mycological Typing Technique, Peritoneal Disease, Polymerase Chain Reaction, Risk Factor, Critical Care and Intensive Care Medicine |
| الوصف: | Introduction: intra-abdominal candidiasis (IAC) may include Candida involvement of peritoneum or intra-abdominal abscess and is burdened by high morbidity and mortality rates in surgical patients. Unfortunately, international guidelines do not specifically address this particular clinical setting due to heterogeneity of definitions and scant direct evidence. In order to cover this unmet clinical need, the Italian Society of Intensive Care and the International Society of Chemotherapy endorsed a project aimed at producing practice recommendations for the management of immune-competent adult patients with IAC. Methods: A multidisciplinary expert panel of 22 members (surgeons, infectious disease and intensive care physicians) was convened and assisted by a methodologist between April 2012 and May 2013. Evidence supporting each statement was graded according to the European Society of Clinical Microbiology and Infection Diseases (ESCMID) grading system. Results: Only a few of the numerous recommendations can be summarized in the Abstract. Direct microscopy examination for yeast detection from purulent and necrotic intra-abdominal specimens during surgery or by percutaneous aspiration is recommended in all patients with nonappendicular abdominal infections including secondary and tertiary peritonitis. Samples obtained from drainage tubes are not valuable except for evaluation of colonization. Prophylactic usage of fluconazole should be adopted in patients with recent abdominal surgery and recurrent gastrointestinal perforation or anastomotic leakage. Empirical antifungal treatment with echinocandins or lipid formulations of amphotericin B should be strongly considered in critically ill patients or those with previous exposure to azoles and suspected intra-abdominal infection with at least one specific risk factor for Candida infection. In patients with nonspecific risk factors, a positive mannan/antimannan or (1→3)-Î2-d-glucan (BDG) or polymerase chain reaction (PCR) test result should be present to start ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/24105327; volume:39; issue:12; firstpage:2092; lastpage:2106; numberofpages:15; journal:INTENSIVE CARE MEDICINE; http://hdl.handle.net/11568/871610Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84888173768 |
| DOI: | 10.1007/s00134-013-3109-3 |
| الإتاحة: | https://doi.org/10.1007/s00134-013-3109-3Test http://hdl.handle.net/11568/871610Test |
| رقم الانضمام: | edsbas.DC5F82FE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00134-013-3109-3 |
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