دورية أكاديمية
Interhemispheric coherence of EEG rhythms in children: Maturation and differentiation in corpus callosum dysgenesis
| العنوان: | Interhemispheric coherence of EEG rhythms in children: Maturation and differentiation in corpus callosum dysgenesis |
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| المؤلفون: | Guillou, J., Duprez, J., Nabbout, R., Kamińska, Anna, Napuri, S., Gomes, C., Kuchenbuch, M., Sauleau, P. |
| المساهمون: | Centre Hospitalier Universitaire Rennes, Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Structure Fédérative de Recherche Necker (UAR 3633 / US24), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Maladies neurodéveloppementales et neurovasculaires (NeuroDiderot (UMR_S_1141 / U1141)), Ingénierie Moléculaire, Cellulaire et Physiopathologie (IMOPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy) |
| المصدر: | ISSN: 0987-7053 ; Neurophysiologie Clinique = Clinical Neurophysiology ; https://hal.science/hal-04574528Test ; Neurophysiologie Clinique = Clinical Neurophysiology, 2024, 54 (3), pp.102981. ⟨10.1016/j.neucli.2024.102981⟩. |
| بيانات النشر: | HAL CCSD Elsevier Masson |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Corpus callosum, Dysgenesis, Audiology, Biomarker, Fractional anisotropy, Cohort, Electroencephalography, Medicine, Psychology, Neuroscience, Magnetic resonance imaging, Internal medicine, Diffusion MRI, Biology, Anatomy, Radiology, Biochemistry, Brain development, Childhood EEG, Corpus callosum dysgenesis, EEG background activity, Sleep spindles, [SDV.IB]Life Sciences [q-bio]/Bioengineering |
| الوصف: | International audience ; Objectives: To evaluate the evolution of interhemispheric coherences (ICo) in background and spindle frequency bands during childhood and use it to identify individuals with corpus callosum dysgenesis (CCd).Methods: A monocentric cohort of children aged from 0.25 to 15 years old, consisting of 13 children with CCd and 164 without, was analyzed. The ICo of background activity (ICOBckgrdA), sleep spindles (ICOspindles), and their sum (sICO) were calculated. The impact of age, gender, and CC status on the ICo was evaluated, and the sICO was used to discriminate children with or without CCd.Results: ICOBckgrdA, ICOspindles and sICO increased significantly with age without any effect of gender (p < 10-4), in both groups. The regression equations of the different ICo were stronger, with adjusted R2 values of 0.54, 0.35, and 0.57, respectively. The ICo was lower in children with CCd compared to those without CCd (p < 10-4 for all comparisons). The area under the precision recall curves for predicting CCd using sICO was 0.992 with 98.9 % sensitivity and 87.5 % specificity.Discussion: ICo of spindles and background activity evolve in parallel to brain maturation and depends on the integrity of the corpus callosum. sICO could be an effective diagnostic biomarker for screening children with interhemispheric dysfunction. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/38703488; hal-04574528; https://hal.science/hal-04574528Test; PUBMED: 38703488 |
| DOI: | 10.1016/j.neucli.2024.102981 |
| الإتاحة: | https://doi.org/10.1016/j.neucli.2024.102981Test https://hal.science/hal-04574528Test |
| رقم الانضمام: | edsbas.DB9E9120 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.neucli.2024.102981 |
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