دورية أكاديمية
Plasma vitamin C levels: risk factors for deficiency and association with self-reported functional health in the European Prospective Investigation into Cancer-Norfolk.
| العنوان: | Plasma vitamin C levels: risk factors for deficiency and association with self-reported functional health in the European Prospective Investigation into Cancer-Norfolk. |
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| المؤلفون: | McCall, S, Clark, AB, Luben, RN, Wareham, NJ, Khaw, KT, Myint, PK |
| بيانات النشر: | MDPI |
| سنة النشر: | 2019 |
| المجموعة: | Oxford University Research Archive (ORA) |
| الوصف: | Background: To investigate the demographic and lifestyles factors associated with vitamin C deficiency and to examine the association between plasma vitamin C level and self-reported physical functional health. Methods: A population-based cross-sectional study using the European Prospective Investigation into Cancer-Norfolk study. Plasma vitamin C level <11 µmol/L indicated vitamin C deficiency. Unconditional logistic regression models assessed the association between vitamin C deficiency and potential risk factors. Associations between quartiles of vitamin C and self-reported functional health measured by Short Form-36 were assessed. Results: After adjustment, vitamin C deficiency was associated with older age, being male, lower physical activity, smoking, more socially deprived area (Townsend index) and a lower educational attainment. Those in the lowest quartile of vitamin C compared to the highest were more likely to score in the lowest decile of physical function [adjusted odd ratio(aOR): 1.43 (95%CI:1.21-1.70)], bodily pain[aOR: 1.29 (95% CI: 1.07-1.56)], general health[aOR: 1.4 (95%CI:1.18-1.66)] and vitality[aOR: 1.23 (95%CI: 1.04-1.45)] SF-36 scores. Conclusions: Simple public health interventions should be aimed at populations with risk factors for vitamin C deficiency. Poor self-reported functional health was associated with lower plasma vitamin C levels, which may reflect symptoms of latent scurvy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://ora.ox.ac.uk/objects/uuid:7b31d454-eebb-4a9d-9195-3905b4b73044Test; https://doi.org/10.3390/nu11071552Test |
| DOI: | 10.3390/nu11071552 |
| الإتاحة: | https://doi.org/10.3390/nu11071552Test https://ora.ox.ac.uk/objects/uuid:7b31d454-eebb-4a9d-9195-3905b4b73044Test |
| حقوق: | info:eu-repo/semantics/openAccess ; CC Attribution (CC BY) |
| رقم الانضمام: | edsbas.DAB9B499 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/nu11071552 |
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