رسالة جامعية
Efeito do jejum intermitente associado ao treinamento aeróbico sobre a saúde e o desempenho físico de ratos wistar
العنوان: | Efeito do jejum intermitente associado ao treinamento aeróbico sobre a saúde e o desempenho físico de ratos wistar |
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المؤلفون: | Dorand, Victor Augusto Mathias |
المساهمون: | Aquino, Jailane de Souza, http://lattes.cnpq.br/8153908179932184Test |
بيانات النشر: | Universidade Federal da Paraíba Brasil Ciências da Nutrição Programa de Pós-Graduação em Ciências da Nutrição UFPB |
سنة النشر: | 2024 |
المجموعة: | Universidade Federal da Paraiba: Biblioteca Digital de Teses e Dissertações |
مصطلحات موضوعية: | Jejum intermitente, Desempenho físico, Exercício aeróbico, Resistência à insulina, Malondialdeído, Dano muscular, Intermittent fasting, Physical performance, Aerobic exercise, Insulin resistance, Malondialdehyde, CNPQ::CIENCIAS DA SAUDE::NUTRICAO |
الوصف: | Intermittent fasting (IF) is characterized by the abstention from food intake, with the duration varying according to the protocol, with time-restricted feeding being one of the most popular protocols. The effects of this intervention are still controversial, with evidence of fat loss, but also potential deterioration in physical performance. Furthermore, most IF studies focus on the treatment or prevention of chronic diseases, meaning there is a lack of research on healthy individuals, whether or not combined with exercise. Considering these aspects, the objective was to evaluate parameters related to physical performance and health, such as body composition, metabolic parameters like lipid, glucose, and hormonal profiles, as well as inflammatory and oxidative parameters in Wistar rats subjected to IF, with or without aerobic training. A total of 40 healthy Wistar rats, approximately 140 days old, were used in the study and randomized into four groups: sedentary controls (SC) and trained (TC), and those subjected to sedentary fasting (SIF) and trained fasting (TIF). The SIF and TIF groups followed a time-restricted fasting protocol (15 hours fasting, 9 hours feeding) for 4 weeks. Simultaneously, the trained groups engaged in treadmill running 5 times a week, with each session lasting 30 minutes. Performance tests were conducted at the beginning and end of the exercise protocol. At the end of the experiment, somatic parameters, food consumption, muscular histology, as well as lipid profile, insulin, leptin, alpha-1-acid glycoprotein, C-reactive protein (CRP), markers of muscle damage, and oxidative markers were evaluated. The TIF group showed body weight loss (-16g ± 6.12g) and lower lean mass (22.49%), LDL (43%), HOMA-IR (29%), and LDH (48%), as well as higher MDA (53%) and CAT (75%) compared to TC group, which had body weight (10.63g ± 7.76g), lean mass (25.78 ± 1.51), LDL (18.86 ± 1.60), HOMA-IR (21.79 ± 1.97), LDH (5582 ± 756), MDA (3.70 ± 0.19), and CAT (14.98 ± 2.41). The TIF group also exhibited reduced ... |
نوع الوثيقة: | thesis |
اللغة: | Portuguese |
العلاقة: | https://repositorio.ufpb.br/jspui/handle/123456789/30130Test |
الإتاحة: | https://repositorio.ufpb.br/jspui/handle/123456789/30130Test |
حقوق: | Acesso aberto ; Attribution-NoDerivs 3.0 Brazil ; http://creativecommons.org/licenses/by-nd/3.0/brTest/ |
رقم الانضمام: | edsbas.D8FF7E08 |
قاعدة البيانات: | BASE |
الوصف غير متاح. |