دورية أكاديمية
Disordered Balance of T-Cell Subsets in Arterial Tertiary Lymphoid Organs in Immunoglobulin G4-Related Vascular Disease.
العنوان: | Disordered Balance of T-Cell Subsets in Arterial Tertiary Lymphoid Organs in Immunoglobulin G4-Related Vascular Disease. |
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المؤلفون: | Kasashima, Satomi, Kawashima, Atsuhiro, Kurose, Nozomu, Ozaki, Satoru, Kasashima, Fuminori, Matsumoto, Yasushi, Takemura, Hirofumi, Ikeda, Hiroko, Harada, Ken-Ichi |
المصدر: | J Am Heart Assoc ; ISSN:2047-9980 ; Volume:12 ; Issue:24 |
بيانات النشر: | Atypon |
سنة النشر: | 2023 |
المجموعة: | PubMed Central (PMC) |
مصطلحات موضوعية: | arterial tertiary lymphoid tissues, follicular helper T cells, follicular regulatory T cells, germinal center, immunoglobulin G4–related abdominal aortic aneurysm, immunoglobulin G4–related disease |
الوصف: | Arterial/aortic tertiary lymphoid organs (ATLOs), characterized by germinal centers, control local arterial immune responses. T follicular helper cells (Tfh), resident in germinal centers, regulate immunoglobulin production and germinal center development. They consist of Tfh1, Tfh2, and Tfh17 subsets. T follicular regulatory (Tfr) cells possess suppressive functions as regulatory T cells and migrate into germinal centers. Immunoglobulin G4 (IgG4)-related diseases manifest in vascular lesions as frequently formed inflammatory aneurysms (IgG4-related abdominal aortic aneurysm [IgG4-AAAs]). IgG4-AAAs contain several ATLOs. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
العلاقة: | https://doi.org/10.1161/JAHA.123.030356Test; https://pubmed.ncbi.nlm.nih.gov/38063185Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863754Test/ |
DOI: | 10.1161/JAHA.123.030356 |
الإتاحة: | https://doi.org/10.1161/JAHA.123.030356Test https://pubmed.ncbi.nlm.nih.gov/38063185Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863754Test/ |
رقم الانضمام: | edsbas.D8F56A7E |
قاعدة البيانات: | BASE |
DOI: | 10.1161/JAHA.123.030356 |
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