دورية أكاديمية
Role of flow magnetic resonance imaging in the monitoring of facial allotransplantations: preliminary results on graft vasculopathy
| العنوان: | Role of flow magnetic resonance imaging in the monitoring of facial allotransplantations: preliminary results on graft vasculopathy |
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| المؤلفون: | Bettoni, Jérémie, Balédent, Olivier, Petruzzo, Palmina, Duisit, Jérôme, Kanitakis, Jean, Devauchelle, Bernard, Lengelé, Benoit, Constans, Jean-Marc, Morelon, Emmanuel, Dakpé, Stéphanie |
| المساهمون: | CHU Amiens-Picardie, CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516 (CHIMERE), Université de Picardie Jules Verne (UPJV), Hospices Civils de Lyon (HCL), University of Cagliari, Université Catholique de Louvain = Catholic University of Louvain (UCL), Hôpital Edouard Herriot CHU - HCL, Lymphocytes B effecteurs et à mémoire – Effector and memory B cells, Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), ANR-10-EQPX-0001,FIGURES,TECHNOLOGIES INNOVANTES ET DEFIGURATION Images, Gestes, Fonctions (Facing Faces Insitute GUiding RESearch)(2010) |
| المصدر: | ISSN: 0901-5027. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2020 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | arteries, follow-up studies, graft rejection, haemodynamics, magnetic resonance imaging, vascularized composite allotransplantation, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Chronic vascular rejection characterized by the myointimal proliferation of smooth muscle cells that progressively obstruct the arterial graft lumen may become the main cause of long-term graft loss in vascularized composite allotransplantation (VCA), as observed in solid organ transplantation. As such, new diagnostic tools are required. The objective of this study was to evaluate the usefulness of flow magnetic resonance imaging (MRI) in the qualitative and quantitative monitoring of VCA in three patients transplanted between 2005 and 2012. Seven flow MRI acquisitions were performed concurrently with standardized clinical and histological monitoring between 2015 and 2017. A progressive reduction in the average flow rate and intraluminal diameter of the arterial pedicle of the grafts was demonstrated. During follow-up, two patients developed chronic vascular rejection requiring partial resection of the graft. For these patients, flow MRI acquisitions were characterized by a significant reduction in vascular signal, with a reduction in intravascular flow prior to anatomical injury. The results of this study confirm the feasibility of reproducible, non-invasive, and non-operator-dependent morphometric and haemodynamic radiological analysis, providing clinicians with new information on the vascular status of VCA over time and offering the prospect of an imaging technique specific to vascular outflow. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31235388; hal-03489857; https://hal.science/hal-03489857Test; https://hal.science/hal-03489857/documentTest; https://hal.science/hal-03489857/file/S0901502719311609.pdfTest; PII: S0901-5027(19)31160-9; PUBMED: 31235388 |
| DOI: | 10.1016/j.ijom.2019.05.003 |
| الإتاحة: | https://doi.org/10.1016/j.ijom.2019.05.003Test https://hal.science/hal-03489857Test https://hal.science/hal-03489857/documentTest https://hal.science/hal-03489857/file/S0901502719311609.pdfTest |
| حقوق: | http://creativecommons.org/licenses/by-ncTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.D80C1879 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.ijom.2019.05.003 |
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