التفاصيل البيبلوغرافية
| العنوان: |
Diagnosis of Schistosoma infection in non-human animal hosts: A systematic review and meta-analysis |
| المؤلفون: |
Liang, Song, Ponpetch, Keerati, Zhou, Yi-Biao, Guo, Jiagang, Erko, Berhanu, Stothard, J Russell, Murad, M Hassan, Zhou, Xiao-Nong, Satrija, Fadjar, Webster, Joanne P, Remais, Justin V, Utzinger, Jürg, Garba, Amadou |
| المساهمون: |
Petersen, Christine A |
| المصدر: |
PLOS Neglected Tropical Diseases, vol 16, iss 5 |
| بيانات النشر: |
eScholarship, University of California |
| سنة النشر: |
2022 |
| المجموعة: |
University of California: eScholarship |
| مصطلحات موضوعية: |
Biomedical and Clinical Sciences, Infection, Good Health and Well Being, Animals, Feces, Prevalence, Reference Standards, Schistosoma, Schistosomiasis, Sensitivity and Specificity, Biological Sciences, Medical and Health Sciences, Tropical Medicine, Health sciences |
| الوصف: |
BackgroundReliable and field-applicable diagnosis of schistosome infections in non-human animals is important for surveillance, control, and verification of interruption of human schistosomiasis transmission. This study aimed to summarize uses of available diagnostic techniques through a systematic review and meta-analysis.Methodology and principal findingsWe systematically searched the literature and reports comparing two or more diagnostic tests in non-human animals for schistosome infection. Out of 4,909 articles and reports screened, 19 met our inclusion criteria, four of which were considered in the meta-analysis. A total of 14 techniques (parasitologic, immunologic, and molecular) and nine types of non-human animals were involved in the studies. Notably, four studies compared parasitologic tests (miracidium hatching test (MHT), Kato-Katz (KK), the Danish Bilharziasis Laboratory technique (DBL), and formalin-ethyl acetate sedimentation-digestion (FEA-SD)) with quantitative polymerase chain reaction (qPCR), and sensitivity estimates (using qPCR as the reference) were extracted and included in the meta-analyses, showing significant heterogeneity across studies and animal hosts. The pooled estimate of sensitivity was 0.21 (95% confidence interval (CI): 0.03-0.48) with FEA-SD showing highest sensitivity (0.89, 95% CI: 0.65-1.00).Conclusions/significanceOur findings suggest that the parasitologic technique FEA-SD and the molecular technique qPCR are the most promising techniques for schistosome diagnosis in non-human animal hosts. Future studies are needed for validation and standardization of the techniques for real-world field applications. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| العلاقة: |
qt85s9q80x; https://escholarship.org/uc/item/85s9q80xTest |
| الإتاحة: |
https://escholarship.org/uc/item/85s9q80xTest |
| حقوق: |
public |
| رقم الانضمام: |
edsbas.D761BD6A |
| قاعدة البيانات: |
BASE |
