دورية أكاديمية
Prenatal diagnosis of total and partial anomalous pulmonary venous connection: multicenter cohort study and meta-analysis
العنوان: | Prenatal diagnosis of total and partial anomalous pulmonary venous connection: multicenter cohort study and meta-analysis |
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المؤلفون: | Paladini D., Pistorio A., Wu L. H., Meccariello G., Lei T., Tuo G., Donarini G., Marasini M., Xie H. -N. |
المساهمون: | Paladini, D., Pistorio, A., Wu, L. H., Meccariello, G., Lei, T., Tuo, G., Donarini, G., Marasini, M., Xie, H. -N. |
سنة النشر: | 2018 |
المجموعة: | IRIS Università degli Studi di Napoli Federico II |
مصطلحات موضوعية: | anomalous venous connection, echocardiography, fetu, meta-analysis of IPD, scimitar syndrome, Female, Gestational Age, Heart Defects, Congenital, Human, Pregnancy, Pregnancy Outcome, Pulmonary Vein, Retrospective Studie, Doppler, Color, Prenatal Diagnosis |
الوصف: | Objectives: The aims of this study were to review systematically literature on and describe the sonographic features and associated anomalies of total (TAPVC) and partial (PAPVC) anomalous pulmonary venous connection and scimitar syndrome (SS). Methods: A retrospective cohort study was carried out of cases of TAPVC, PAPVC and SS that underwent comprehensive ultrasound examination, seen over a 20-year period at two tertiary referral centers. Assessed variables included TAPVC subtype, gestational age at diagnosis, area behind the left atrium, ventricular disproportion, vertical vein, pulmonary venous obstruction, mode of diagnosis, association with cardiac and extracardiac conditions, and pregnancy and fetoneonatal outcomes. The outcome was considered favorable if the individual was alive and well (no functional impairment from surgery or cardiac or extracardiac conditions). Cases associated with right isomerism were excluded from the analysis, as TAPVC in these cases was only one of several major cardiac anomalies affecting sonographic signs. A systematic review was performed in order to obtain a synthesis of characteristics associated with TAPVC, PAPVC and SS. The literature search of PubMed and EMBASE (1970–2016) included reviews, case series and case reports. A meta-analysis was conducted only for TAPVC. Random-effects models were used to obtain pooled estimates of the frequencies of clinical characteristics and sonographic features. Results: For TAPVC, a total of 15 studies involving 71 patients (including 13 from the current cohort study) were included in the systematic review and meta-analysis. The pooled estimate for the association of TAPVC with congenital heart disease was 28.3% (95% CI, 18.1–41.3%) and with extracardiac anomalies it was 18.5% (95% CI, 10.5–30.6%). Of TAPVC cases, obstructed venous return was observed in 34.1% (95% CI, 22.7–47.7%), a favorable outcome in 43.8% (95% CI, 24.0–65.8%), ventricular disproportion in 59.2% (95% CI, 45.1–72.0%), increased area behind the left atrium in 58.1% ... |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000437702300005; volume:52; issue:1; firstpage:24; lastpage:34; numberofpages:11; journal:ULTRASOUND IN OBSTETRICS & GYNECOLOGY; http://hdl.handle.net/11588/844229Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85049519469 |
DOI: | 10.1002/uog.18907 |
الإتاحة: | https://doi.org/10.1002/uog.18907Test http://hdl.handle.net/11588/844229Test |
حقوق: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.D657D322 |
قاعدة البيانات: | BASE |
DOI: | 10.1002/uog.18907 |
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