دورية أكاديمية

Automatic Multiparametric Magnetic Resonance Imaging‐Based Prostate Lesions Assessment with Unsupervised Domain Adaptation

التفاصيل البيبلوغرافية
العنوان: Automatic Multiparametric Magnetic Resonance Imaging‐Based Prostate Lesions Assessment with Unsupervised Domain Adaptation
المؤلفون: Dai, Jing, Wang, Xiaomei, Li, Yingqi, Liu, Zhiyu, Ng, Yui-Lun, Xiao, Jiaren, Fan, Joe King Man, Lam, James, Dou, Qi, Vardhanabhuti, Varut, Kwok, Ka-Wai
المساهمون: Innovation and Technology Commission - Hong Kong
المصدر: Advanced Intelligent Systems ; volume 5, issue 9 ; ISSN 2640-4567 2640-4567
بيانات النشر: Wiley
سنة النشر: 2023
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: Multiparametric magnetic resonance imaging (mpMRI) has emerged as a valuable diagnostic tool in prostate lesion assessment. However, training convolutional neural networks (CNNs) inevitably involves magnetic resonance (MR) images from multiple cohorts. There always exists variation in scanning protocol among cohorts, inducing significant changes in data distribution between source and target domains. This challenge has greatly limited clinical adoption on a large scale. Herein, a coarse mask‐guided deep domain adaptation network (CMD 2 A‐Net) is proposed to develop a fully automated framework for prostate lesion detection and classification (PLDC). No category or mask label is required from the target domain. A coarse segmentation module is trained to cover the possible lesion‐related regions, so that attention maps can be generated to dedicate the local feature extraction of lesions within those regions. Experiments are performed on 512 mpMRI sets from datasets of PROSTATEx (330 sets) and two cohorts, A (74 sets) and B (108 sets). Using ensemble learning, CMD 2 A‐Net accomplishes an AUC of 0.921 in cohort A and 0.913 in cohort B, demonstrating its transferability from a large‐scale public dataset PROSTATEx to small‐scale target domains. Results from an ablation study also support its effectiveness in classification between benign and malignant lesions, compared to the state‐of‐the‐art models. An interactive preprint version of the article can be found here: https://doi.org/10.22541/au.166081031.11420810/v1Test .
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1002/aisy.202200246
الإتاحة: https://doi.org/10.1002/aisy.202200246Test
حقوق: http://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.D58AA6BD
قاعدة البيانات: BASE