مؤتمر
Impact of the UK lockdown on early COPD
| العنوان: | Impact of the UK lockdown on early COPD |
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| المؤلفون: | Donaldson, GC, Ritchie, AI, McLean, F, King, B, Yip, K, Beech, AS, Bikov, A, Jenkins, AR, Deans, A, Bolton, CE, Calverley, PM, Choudhury, G, McGarvey, L, Sapey, E, Vestbo, J, Wedzicha, JA |
| المساهمون: | Novartis Pharma Ag, Boehringer Ingelheim Pharma Gmbh & Co KG, AstraZeneca UK Limited, Chiesi Farmaceutici S.P.A, GlaxoSmithKline Services Unlimited |
| المصدر: | International Conference of the American-Thoracic-Society (ATS) ; 2 ; 1 |
| بيانات النشر: | AMER THORACIC SOC |
| سنة النشر: | 2021 |
| المجموعة: | Imperial College London: Spiral |
| مصطلحات موضوعية: | Science & Technology, Life Sciences & Biomedicine, Critical Care Medicine, Respiratory System, General & Internal Medicine, 11 Medical and Health Sciences |
| جغرافية الموضوع: | ELECTR NETWORK |
| الوصف: | INTRODUCTION: Public health measures to reduce the transmission of COVID-19 have required various changes in life-style, including loss or risk to employment and social isolation. We wished to assess how these measured effected 30-45 year old smokers at risk of COPD participating in the BLF Early COPD cohort study METHODS: At enrolment, participants were aged 30-45 years, tobacco smokers with >10 pack-year smoking history, FEV1=>80% predicted and a BMI < 35kg/m2. Participants were seen face-to-face in clinic pre-COVID. During lock-down, they were posted questionnaires and contacted by telephone. The last clinic visit took place on the 12 March 2020, remote visits took place between 16 April and 28 Sep. 260 individuals at six sites (25 Belfast, 38 Birmingham, 25 Edinburgh, 101 London, 27 Manchester and 44 Nottingham) were asked about smoking habits. The MRC chronic bronchitis questionnaire, COPD Assessment test (CAT), Leicester cough questionnaire, Hospital Anxiety and Depression questionnaire were completed in writing by the participant and returned by post or photographed and returned by email. At enrolment, the post-BD FEV1 was 3.81 (SD 0.8) litres, 101% (11) of GLI predicted. Comparisons were made by paired t-tests and chi-squared tests. RESULTS: Level of anxiety increased from 6.74 (SD 4.4) to 7.37 (SD 4.7, n=233; p=0.010) during lock-down; depression scores increased from 4.30 (3.9) to 5.14 (SD 4.1; n=233; p<0.001). Anxiety increased in 78/233 and depression in 89/233 participants by 2 or more units, 2 units is considered the minimally important (MCID) in bronchiectasis, COPD and ILD (Wynne, 2020) Figure 1 shows that during lock-down, the proportion of participants not smoking increased from 31/259 (12.0%) to 62/259 (23.9%; p<0.001). In those who continued to smoke, cigarettes per day (p=0.59) and rolling tobacco consumption (g/week) (p=0.92) were unchanged. Participants reported less chronic bronchitis defined as “do you bring up phlegm like this on most days (or nights) as much as three ... |
| نوع الوثيقة: | conference object |
| اللغة: | unknown |
| تدمد: | 1073-449X |
| العلاقة: | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE; http://hdl.handle.net/10044/1/93959Test; C028-3002979185; PO 6101188364; PO 7100013120; PO 4500248634; PO6600145677 |
| DOI: | 10.1164/ajrccm-conference.2021.203.1_MeetingAbstracts.A1768 |
| الإتاحة: | https://doi.org/10.1164/ajrccm-conference.2021.203.1_MeetingAbstracts.A1768Test http://hdl.handle.net/10044/1/93959Test |
| حقوق: | ©The authors 2021 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: | edsbas.D4FFC87 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 1073449X |
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| DOI: | 10.1164/ajrccm-conference.2021.203.1_MeetingAbstracts.A1768 |