دورية أكاديمية
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage
| العنوان: | Global phylogeography and ancient evolution of the widespread human gut virus crAssphage |
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| المؤلفون: | Edwards, Robert, Vega, Alejandro, Norman, Holly, Ohaeri, Maria, Levi, Kyle, Dinsdale, Elizabeth, Cinek, Ondrej, Aziz, Ramy, Mcnair, Katelyn, Barr, Jeremy, Bibby, Kyle, Brouns, Stan, Cazares, Adrian, de Jonge, Patrick, Desnues, Christelle, Díaz Muñoz, Samuel, Fineran, Peter, Kurilshikov, Alexander, Lavigne, Rob, Mazankova, Karla, Mccarthy, David, Nobrega, Franklin, Reyes Muñoz, Alejandro, Tapia, German, Trefault, Nicole, Tyakht, Alexander, Vinuesa, Pablo, Wagemans, Jeroen, Zhernakova, Alexandra, Aarestrup, Frank, Ahmadov, Gunduz, Alassaf, Abeer, Anton, Josefa, Asangba, Abigail, Billings, Emma, Cantu, Adrian, Carlton, Jane, Cazares, Daniel, Cho, Gyu-Sung, Condeff, Tess, Cortés, Pilar, Cranfield, Mike, Cuevas, Daniel, de La Iglesia, Rodrigo, Decewicz, Przemyslaw, Doane, Michael, Dominy, Nathaniel, Dziewit, Lukasz, Elwasila, Bashir Mukhtar, Eren, A. Murat, Franz, Charles, M. A. P., Fu, Jingyuan, Garcia-Aljaro, Cristina, Ghedin, Elodie, Gulino, Kristen, Haggerty, John, Head, Steven, Hendriksen, Rene, S, Hill, Colin, Hyöty, Heikki, Ilina, Elena, Irwin, Mitchell, Jeffries, Thomas, Jofre, Juan, Junge, Randall, Kelley, Scott, Khan Mirzaei, Mohammadali, Kowalewski, Martin, Kumaresan, Deepak, Leigh, Steven, Lipson, David, Lisitsyna, Eugenia, Llagostera, Montserrat, Maritz, Julia, Marr, Linsey, Mccann, Angela, Molshanski-Mor, Shahar, Monteiro, Sílvia, Moreira-Grez, Benjamin, Morris, Megan, Mugisha, Lawrence, Muniesa, Maite, Neve, Horst, H., Nguyen, Nam-Phuong, Nigro, Olivia, Nilsson, Anders, O’connell, Taylor, Odeh, Rasha, Oliver, Andrew, Piuri, Maria, Prussin Ii, Aaron, Qimron, Udi, Quan, Zhe-Xue, Rainetova, Petra, Ramírez-Rojas, Adán, Raya, Raul, Reasor, Kim, Rice, Gillian, Rossi, Alessandro, Santos, Ricardo, Shimashita, John, Stachler, Elyse, Stene, Lars, Strain, Ronan, Stumpf, Rebecca, Torres, Pedro, Twaddle, Alan, Ugochi Ibekwe, Maryann, Villagra, Nicolás, Wandro, Stephen, White, Bryan, White, Andy, White, Katrine, Wijmenga, Cisca, Zambrano, Maria, Zschach, Henrike, Dutilh, Bas, E |
| المساهمون: | San Diego State University (SDSU), Consejo Nacional de Investigaciones Científicas y Técnicas Buenos Aires (CONICET), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Laboratory of Gene Technology, Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), Monash University Clayton, University Medical Center Groningen Groningen (UMCG), Centro de Investigación Oceanográfica en el Pacífico Sur Oriental (COPAS), Universidad de Concepción - University of Concepcion Chile, Dartmouth College Hanover, Marine Biological Laboratory (MBL), University of Chicago, Department of Safety and Quality of Fruit and Vegetables, Federal Research Institute for Nutrition and Food, Department of Parasite and Virus Genomics, The Institute for Genomic Research (TIGR), The Scripps Research Institute La Jolla, San Diego, Danmarks Tekniske Universitet = Technical University of Denmark (DTU), Queen's University Belfast (QUB), Hawkesbury Institute for the Environment Richmond (HIE), Western Sydney University, CREW - Center for Research on the English-speaking World - EA 4399 (CREW), Université Sorbonne Nouvelle - Paris 3, School of Microbiology, University College Cork (UCC), Université du Cap-Vert, université du Cap-Vert, Department of Microbiology University of Barcelona, Dept Microbiol & Biotechnol, Max Rubner Inst, Department of Pharmaceutical Biosciences, Uppsala University, University of Manchester Manchester, Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology Zürich (ETH Zürich), Getulio Vargas Foundation, Centro Geofísico de Canarias, Instituto Geografico Nacional, Laboratorio de Patogénesis Molecular y Antimicrobianos, Facultad de Medicina , Universidad Andres Bello, University of Illinois, University of Illinois System, National Severe Storms Laboratory (NSSL), National Oceanic and Atmospheric Administration (NOAA), Department of Medical Genetics, HMNC Brain Health, Universiteit Utrecht / Utrecht University Utrecht |
| المصدر: | ISSN: 2058-5276. |
| بيانات النشر: | HAL CCSD Nature Publishing Group |
| سنة النشر: | 2019 |
| المجموعة: | Université de Toulon: HAL |
| مصطلحات موضوعية: | Bacteriophages, Environmental microbiology, Microbiome, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology |
| الوصف: | International audience ; Microbiomes are vast communities of microorganisms and viruses that populate all natural ecosystems. Viruses have been considered to be the most variable component of microbiomes, as supported by virome surveys and examples of high genomic mosaicism. However, recent evidence suggests that the human gut virome is remarkably stable compared with that of other environments. Here, we investigate the origin, evolution and epidemiology of crAssphage, a widespread human gut virus. Through a global collaboration, we obtained DNA sequences of crAssphage from more than one-third of the world’s countries and showed that the phylogeography of crAssphage is locally clustered within countries, cities and individuals. We also found fully colinear crAssphage-like genomes in both Old-World and New-World primates, suggesting that the association of crAssphage with primates may be millions of years old. Finally, by exploiting a large cohort of more than 1,000 individuals, we tested whether crAssphage is associated with bacterial taxonomic groups of the gut microbiome, diverse human health parameters and a wide range of dietary factors. We identified strong correlations with different clades of bacteria that are related to Bacteroidetes and weak associations with several diet categories, but no significant association with health or disease. We conclude that crAssphage is a benign cosmopolitan virus that may have coevolved with the human lineage and is an integral part of the normal human gut virome. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-02195894; https://amu.hal.science/hal-02195894Test; https://amu.hal.science/hal-02195894/documentTest; https://amu.hal.science/hal-02195894/file/nihms-1595144.pdfTest; PUBMEDCENTRAL: PMC7440971 |
| DOI: | 10.1038/s41564-019-0494-6 |
| الإتاحة: | https://doi.org/10.1038/s41564-019-0494-6Test https://amu.hal.science/hal-02195894Test https://amu.hal.science/hal-02195894/documentTest https://amu.hal.science/hal-02195894/file/nihms-1595144.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.D3F185C0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41564-019-0494-6 |
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