دورية أكاديمية
Transport of L-Arginine Related Cardiovascular Risk Markers
| العنوان: | Transport of L-Arginine Related Cardiovascular Risk Markers |
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| المؤلفون: | Banjarnahor, Sofna, Rodionov, Roman N., König, Jörg, Maas, Renke |
| سنة النشر: | 2020 |
| المجموعة: | OPUS FAU - Online publication system of Friedrich-Alexander-Universität Erlangen-Nürnberg |
| مصطلحات موضوعية: | ddc:610 |
| الوصف: | L-arginine and its derivatives, asymmetric and symmetric dimethylarginine (ADMA and SDMA) and L-homoarginine, have emerged as cardiovascular biomarkers linked to cardiovascular outcomes and various metabolic and functional pathways such as NO-mediated endothelial function. Cellular uptake and efflux of L-arginine and its derivatives are facilitated by transport proteins. In this respect the cationic amino acid transporters CAT1 and CAT2 (SLC7A1 and SLC7A2) and the system y+L amino acid transporters (SLC7A6 and SLC7A7) have been most extensively investigated, so far, but the number of transporters shown to mediate the transport of L-arginine and its derivatives is constantly increasing. In the present review we assess the growing body of evidence regarding the function, expression, and clinical relevance of these transporters and their possible relation to cardiovascular diseases. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/15502Test; urn:nbn:de:bvb:29-opus4-155028; https://nbn-resolving.org/urn:nbn:de:bvb:29-opus4-155028Test; https://doi.org/10.3390/jcm9123975Test; https://opus4.kobv.de/opus4-fau/files/15502/jcm-09-03975-v2.pdfTest |
| DOI: | 10.3390/jcm9123975 |
| الإتاحة: | https://doi.org/10.3390/jcm9123975Test https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/15502Test https://nbn-resolving.org/urn:nbn:de:bvb:29-opus4-155028Test https://opus4.kobv.de/opus4-fau/files/15502/jcm-09-03975-v2.pdfTest |
| حقوق: | https://creativecommons.org/licenses/by/4.0/deed.deTest ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.D36E93F9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/jcm9123975 |
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