دورية أكاديمية

Deceased Organ Donor Management and Organ Distribution From Organ Procurement Organization-Based Recovery Facilities Versus Acute-Care Hospitals

التفاصيل البيبلوغرافية
العنوان: Deceased Organ Donor Management and Organ Distribution From Organ Procurement Organization-Based Recovery Facilities Versus Acute-Care Hospitals
المؤلفون: Vail, Emily A., Schaubel, Douglas E., Potluri, Vishnu S., Abt, Peter L., Martin, Niels D., Reese, Peter P., Neuman, Mark D.
المساهمون: National Institute of Diabetes and Digestive and Kidney Diseases, Agency for Healthcare Research and Quality
المصدر: Progress in Transplantation ; ISSN 1526-9248 2164-6708
بيانات النشر: SAGE Publications
سنة النشر: 2023
مصطلحات موضوعية: Transplantation
الوصف: Introduction: Organ recovery facilities address the logistical challenges of hospital-based deceased organ donor management. While more organs are transplanted from donors in facilities, differences in donor management and donation processes are not fully characterized. Research Question: Does deceased donor management and organ transport distance differ between organ procurement organization (OPO)-based recovery facilities versus hospitals? Design: Retrospective analysis of Organ Procurement and Transplant Network data, including adults after brain death in 10 procurement regions (April 2017-June 2021). The primary outcomes were ischemic times of transplanted hearts, kidneys, livers, and lungs. Secondary outcomes included transport distances (between the facility or hospital and the transplant program) for each transplanted organ. Results: Among 5010 deceased donors, 51.7% underwent recovery in an OPO-based recovery facility. After adjustment for recipient and system factors, mean differences in ischemic times of any transplanted organ were not significantly different between donors in facilities and hospitals. Transplanted hearts recovered from donors in facilities were transported further than hearts from hospital donors (median 255 mi [IQR 27, 475] versus 174 [IQR 42, 365], P = .002); transport distances for livers and kidneys were significantly shorter ( P < .001 for both). Conclusion: Organ recovery procedures performed in OPO-based recovery facilities were not associated with differences in ischemic times in transplanted organs from organs recovered in hospitals, but differences in organ transport distances exist. Further work is needed to determine whether other observed differences in donor management and organ distribution meaningfully impact donation and transplantation outcomes.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/15269248231212918
الإتاحة: https://doi.org/10.1177/15269248231212918Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.D0D7D217
قاعدة البيانات: BASE