التفاصيل البيبلوغرافية
| العنوان: |
Histone degradation by the proteasome regulates chromatin and cellular plasticity |
| المؤلفون: |
Shmueli, Merav D., Sheban, Daoud, Eisenberg‐Lerner, Avital, Merbl, Yifat |
| المساهمون: |
H2020 Marie Skłodowska-Curie Actions, Israel Science Foundation, H2020 European Research Council |
| المصدر: |
The FEBS Journal ; volume 289, issue 12, page 3304-3316 ; ISSN 1742-464X 1742-4658 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2021 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Histones constitute the primary protein building blocks of the chromatin and play key roles in the dynamic control of chromatin compaction and epigenetic regulation. Histones are regulated by intricate mechanisms that alter their functionality and stability, thereby expanding the regulation of chromatin‐transacting processes. As such, histone degradation is tightly regulated to provide spatiotemporal control of cellular histone abundance. While several mechanisms have been implicated in controlling histone stability, here, we discuss proteasome‐dependent degradation of histones and the protein modifications that are associated with it. We then highlight specific cellular and physiological states that are associated with altered histone degradation by cellular proteasomes. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/febs.15903 |
| الإتاحة: |
https://doi.org/10.1111/febs.15903Test |
| حقوق: |
http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: |
edsbas.D0C99C39 |
| قاعدة البيانات: |
BASE |
