دورية أكاديمية

Cardiac Metastasis in Renal Cell Carcinoma without Vena Cava or Atrial Involvement: an Unusual Presentation of Metastatic Disease

التفاصيل البيبلوغرافية
العنوان: Cardiac Metastasis in Renal Cell Carcinoma without Vena Cava or Atrial Involvement: an Unusual Presentation of Metastatic Disease
المؤلفون: Zhang, Ben, Malouf, Joseph, Young, Phillip, Kohli, Manish, Dronca, Roxana
المصدر: Rare Tumors ; volume 5, issue 3, page 103-105 ; ISSN 2036-3613 2036-3613
بيانات النشر: SAGE Publications
سنة النشر: 2013
مصطلحات موضوعية: Oncology, Histology
الوصف: Cardiac metastasis in renal cell carcinoma is a very rare entity, with only a few previously reported cases. In this series, we report two cases of ventricular metastases from renal cell carcinoma without vena cava or right atrial involvement. The first case involves an initially isolated inoperable metastasis to the left ventricle, which was treated with systemic targeted therapy with favorable local response. Our second case illustrates a patient with an isolated cardiac metastasis in the interventricular septum with extension into the right ventricle, which has also remained stable in size on systemic targeted therapy. Although anti-angiogenic agents such as tyrosine kinase inhibitors have transformed the treatment of metastatic renal cell carcinoma in recent years, their efficacy and safety in treating patients with metastatic disease in highly vascular organs such as the heart are currently unknown, with no prior reports on this topic. We describe our novel management of these unique cases and discuss the current medical and surgical approaches to treating cardiac metastases from renal cell carcinoma.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.4081/rt.2013.e29
الإتاحة: https://doi.org/10.4081/rt.2013.e29Test
حقوق: http://journals.sagepub.com/page/policies/text-and-data-mining-licenseTest
رقم الانضمام: edsbas.D0B106D9
قاعدة البيانات: BASE