دورية أكاديمية
Systematic review of topical interventions for the management of pain in chronic wounds
| العنوان: | Systematic review of topical interventions for the management of pain in chronic wounds |
|---|---|
| المؤلفون: | Ffrench, C, Finn, D, Velligna, A, Ivory, J, Healy, C, Butler, K, Sezgin, D, Carr, P, Probst, S, McLoughlin, A, Arshad, S, McIntosh, C, Gethin, G |
| بيانات النشر: | Wolters Kluwer Health |
| سنة النشر: | 2023 |
| المجموعة: | Griffith University: Griffith Research Online |
| مصطلحات موضوعية: | Pain, Clinical sciences, Neurosciences, Pharmacology and pharmaceutical sciences |
| الوصف: | Chronic wounds adversely affect quality of life. Pain is associated with chronic wounds, and its impact can vary according to wound aetiology, condition, and patient factors. This systematic review examined the effectiveness of topical interventions in the management chronic wound–related pain guided by PRISMA recommendations of randomised controlled trials (RCTs) where pain reduction is the primary outcome. Inclusion criteria were adults (older than 18 years) with chronic venous, arterial, diabetic, or pressure ulcers where pain has been managed through topical administration of pharmacological/nonpharmacological agents. Searches were conducted in Ovid Embase, Ovid MEDLINE, EBSCOhost, CINAHL, CENTRAL, PubMed, Web of Science, and Scopus. Studies were screened for eligibility; risk of bias and data were extracted by 2 independent assessors. Searches retrieved 10,327 titles and abstracts (7760 after deduplication). Nine full texts (1323 participants) examining ibuprofen (n = 4), morphine (n = 2), BWD + PHMB [polihexanide-containing biocellulose wound dressing] (n = 1), and EMLA (n = 2) were included. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool. Meta-analysis was not possible, but initial exploration suggests improved outcomes (reduced pain) for ibuprofen when compared with controls. Two studies involving morphine showed conflicting findings. Included studies often had small samples, and considering confounding factors (eg, comorbidities), the results should be interpreted with caution. Review of included studies suggests that topical interventions may provide pain relief in individuals with chronic wounds. Further adequately powered RCTs are recommended to assess the efficacy of topical interventions for the management of chronic wound–related pain. ; Full Text |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2471-2531 |
| العلاقة: | Pain Reports; Ffrench, C; Finn, D; Velligna, A; Ivory, J; Healy, C; Butler, K; Sezgin, D; Carr, P; Probst, S; McLoughlin, A; Arshad, S; McIntosh, C; Gethin, G, Systematic review of topical interventions for the management of pain in chronic wounds, Pain Reports, 2023, 8 (5), pp. e1073; http://hdl.handle.net/10072/427188Test |
| DOI: | 10.1097/PR9.0000000000001073 |
| الإتاحة: | https://doi.org/10.1097/PR9.0000000000001073Test http://hdl.handle.net/10072/427188Test |
| حقوق: | https://creativecommons.org/licenses/by-nd/4.0Test/ ; © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain. This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0 (CC BY-ND) which allows for redistribution, commercial and noncommercial, as long as it is passed along unchanged and in whole, with credit to the author. ; open access |
| رقم الانضمام: | edsbas.CF60AAEE |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 24712531 |
|---|---|
| DOI: | 10.1097/PR9.0000000000001073 |