التفاصيل البيبلوغرافية
| العنوان: |
Efficacy and safety testing of dissolving microarray patches in Chinese subjects |
| المؤلفون: |
Ma, Yonghao, Li, Chengguo, Mai, Zhuoxian, Yang, Jian, Tai, Meiling, Leng, Gang |
| المصدر: |
Journal of Cosmetic Dermatology ; volume 21, issue 8, page 3496-3502 ; ISSN 1473-2130 1473-2165 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2021 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Objectives There is a lack of clinical research in the Chinese market concerning dissolving microarray (DMA) patches in cosmetic applications. In this study, the clinical efficacy and safety tests of DMA patch technology were performed on Chinese consumers. Methods A 4‐week clinical efficacy and safety evaluation was conducted on 30 Chinese female subjects with crow's feet and eye bags. DMA patches loaded with hyaluronic acid (HA‐DMA) were applied under the eyes and corners of the eyes of the subjects three times a week over four consecutive weeks. Skin firmness and dermal layer strength were measured using ultrasound, and changes in skin wrinkles were detected using VISIA‐CR and Primos Lite. Eye bag ratings were evaluated by professional dermatologists based on the 0–6 grades of eye bags in the “Skin Aging Atlas Volume 2: Asian Type.” Results HA‐DMA patches produced good clinical improvements on both crow's feet and eye bags in the study participants. HA‐DMA effectively increased skin firmness while reducing the number, area, and volume of crow's feet, along with reducing eye bag ratings. The reductions in all metrics were statistically significant with positive effects evident in as little as 1 week of treatment. There were no adverse effects related to the treatments observed during the test period. Conclusions In a clinical efficacy trial of 30 Chinese female subjects, HA‐DMA showed excellent therapeutic benefits without adverse effects while reducing crow's feet and eye bags. HA‐DMA is expected to be a safe, effective, and novel cosmetic for improving the appearance of aging skin. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/jocd.14594 |
| الإتاحة: |
https://doi.org/10.1111/jocd.14594Test |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.CF08E41C |
| قاعدة البيانات: |
BASE |
