دورية أكاديمية
Ginsenoside Rg3 Serves as an Adjuvant Chemotherapeutic Agent and VEGF Inhibitor in the Treatment of Non-Small Cell Lung Cancer: A Meta-Analysis and Systematic Review
| العنوان: | Ginsenoside Rg3 Serves as an Adjuvant Chemotherapeutic Agent and VEGF Inhibitor in the Treatment of Non-Small Cell Lung Cancer: A Meta-Analysis and Systematic Review |
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| المؤلفون: | Tao Xu, Zhichao Jin, Yuan Yuan, Huamin Wei, Xinyao Xu, Shulin He, Shuntai Chen, Wei Hou, Qiujun Guo, Baojin Hua |
| المصدر: | Evidence-Based Complementary and Alternative Medicine, Vol 2016 (2016) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2016 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Other systems of medicine, RZ201-999 |
| الوصف: | Objective. To evaluate ginsenoside Rg3 combined with chemotherapy for non-small-cell lung cancer (NSCLC) treatment, in a meta-analysis. Materials and Methods. We searched PubMed, EMBASE, the Cochrane Library, the China National Knowledge Infrastructure, and the VIP and Wanfang databases for eligible studies. We manually searched for printed journals and relevant textbooks. Statistical analyses were performed with Revman 5.3 and STATA 14.0 software packages. Results. Twenty studies were included. Ginsenoside Rg3 combined with chemotherapy could enhance response, improve disease control, prolong overall survival, improve patient quality of life, reduce leucocyte count decrease due to chemotherapy, reduce vascular endothelial growth factor expression in peripheral blood, and increase CD4/CD8 T cell ratio. Conclusion. Ginsenoside Rg3 combined with chemotherapy may enhance short-term efficacy and overall survival, alleviate treatment-induced side effects, reduce vascular endothelial growth factor expression, increase CD4/CD8 T cell ratio, and serve as a potential therapeutic regimen for NSCLC. However, considering the limitations, the conclusion should be interpreted carefully, and these results need to be confirmed by more high-quality trials. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1741-427X 1741-4288 |
| العلاقة: | http://dx.doi.org/10.1155/2016/7826753Test; https://doaj.org/toc/1741-427XTest; https://doaj.org/toc/1741-4288Test; https://doaj.org/article/a912d868fd244d3d9f0ed06285be8ca6Test |
| DOI: | 10.1155/2016/7826753 |
| الإتاحة: | https://doi.org/10.1155/2016/7826753Test https://doaj.org/article/a912d868fd244d3d9f0ed06285be8ca6Test |
| رقم الانضمام: | edsbas.CE9C5BE4 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 1741427X 17414288 |
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| DOI: | 10.1155/2016/7826753 |