كتاب
Management of Hepatocellular Carcinoma in the Setting of Liver Cirrhosis
| العنوان: | Management of Hepatocellular Carcinoma in the Setting of Liver Cirrhosis |
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| المؤلفون: | Giakoustidis, Alexander, Giakoustidis, Dimitrios E. |
| المصدر: | https://www.intechopen.com/books/5960Test. |
| بيانات النشر: | IntechOpen |
| سنة النشر: | 2017 |
| المجموعة: | IntechOpen (E-Books) |
| مصطلحات موضوعية: | Liver Cirrhosis - Update and Current Challenges |
| الوصف: | Cirrhosis is an increasing cause of morbidity and mortality in more developed countries, being the 14th most common cause of death worldwide. Hepatocellular carcinoma (HCC) consists a significant health issue worldwide, responsible for more than 1 million deaths annually. The incidence and mortality rates vary across different geographical areas. Between 60 and 90% of HCC patients already have liver cirrhosis, attributed mainly to chronic hepatitis B and C, alcohol abuse, and non-alcoholic fatty liver disease (NASH). The surgical management of HCC in the setting of liver cirrhosis with curative intent includes liver resection, ablation or microwave coagulation, and liver transplantation (LT). Liver resection in a cirrhotic liver with HCC is associated with lower survival rates compared with liver transplantation (LT), depending on the diseases’ stage but on the contrary liver resection could be potentially offered in a larger population compared to liver transplantation. One of the biggest limitations of liver resection is the risk of tumor recurrence, which is high, and it may exceed 70% 5 years after the procedure. Liver transplantation is considered the best treatment for hepatocellular carcinoma at early stages because it removes the tumor as well as the underlying cirrhotic liver. |
| نوع الوثيقة: | book part |
| اللغة: | English |
| ردمك: | 978-953-51-3309-4 953-51-3309-8 |
| العلاقة: | https://mts.intechopen.com/articles/show/title/management-of-hepatocellular-carcinoma-in-the-setting-of-liver-cirrhosisTest |
| DOI: | 10.5772/intechopen.68594 |
| الإتاحة: | https://doi.org/10.5772/intechopen.68594Test https://mts.intechopen.com/articles/show/title/management-of-hepatocellular-carcinoma-in-the-setting-of-liver-cirrhosisTest |
| حقوق: | https://creativecommons.org/licenses/by/3.0Test/ |
| رقم الانضمام: | edsbas.C9FD1342 |
| قاعدة البيانات: | BASE |
| ردمك: | 9789535133094 9535133098 |
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| DOI: | 10.5772/intechopen.68594 |