دورية أكاديمية

Characteristics and Evolution of Microbial Drug Resistance in Burned Patients

التفاصيل البيبلوغرافية
العنوان: Characteristics and Evolution of Microbial Drug Resistance in Burned Patients
المؤلفون: Huang, Zhifeng, Wang, Kejian, Gan, Yu, Yang, Kun, Gao, Liangdi, Xiong, Bing, Li, Hanhua, Niu, Xiaohui, Lai, Wen
المساهمون: Medical Scientific Research Foundation of Guangdong Province, Science and Technology Program of Guangzhou, National Natural Science Foundation of Guangdong
المصدر: Journal of Burn Care & Research ; ISSN 1559-047X 1559-0488
بيانات النشر: Oxford University Press (OUP)
سنة النشر: 2024
الوصف: Wound infection is a serious complication in burn injury, which is a common form of trauma and an important public health issue. We investigated samples from burn and nonburn wounds for microbial characteristics and temporal trends of antibiotic resistance. Wound samples were collected from 369 burned patients and 927 non-burned individuals admitted from 2007 to 2017. Higher frequency of Acinetobacter baumannii, Klebsiella pneumonia, and Pseudomonas aeruginosa was observed in samples from burned individuals when compared to those from non-burned. The prevalence of different groups of bacteria varied when the samples were stratified according to age and sex. The antimicrobial resistance profiles showed a significant difference between burned and non-burned patients. The different temporal trends of antimicrobial resistance rates were also found, which may be critical for the proper selection of antibiotics in burn treatment. The present study suggested that frequent pathogens and antibacterial resistance evolution could differ between burn wounds and other wounds. Therefore, periodic surveillance of antibiotic resistance patterns in the burn unit might help physicians properly select antibiotics for treatment.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1093/jbcr/iraa039
DOI: 10.1093/jbcr/iraa039/57435863/iraa039.pdf
الإتاحة: https://doi.org/10.1093/jbcr/iraa039Test
حقوق: https://academic.oup.com/pages/standard-publication-reuse-rightsTest
رقم الانضمام: edsbas.C8F0F12D
قاعدة البيانات: BASE