التفاصيل البيبلوغرافية
| العنوان: |
Translational imaging of the fibroblast activation protein (FAP) using the new ligand [68Ga]Ga-OncoFAP-DOTAGA |
| المؤلفون: |
Backhaus, Philipp, Gierse, F., Burg, M. C., Büther, F., Asmus, I., Dorten, P., Cufe, J., Roll, W., Neri, D., Cazzamalli, S., Millul, J., Mock, J., Galbiati, A., Zana, A., Schäfers, K. P., Hermann, S., Weckesser, M., Tio, J., Wagner, S., Breyholz, H.-J., Schäfers, M. |
| المصدر: |
http://lobid.org/resources/99370678071406441Test#!, 49(6):1822-1832. |
| سنة النشر: |
2021 |
| المجموعة: |
Publisso (ZB MED-Publikationsportal Lebenswissenschaften) |
| مصطلحات موضوعية: |
PET/MRI, PET/CT, Humans [MeSH], Breast cancer, Radiopharmaceuticals [MeSH], Animals [MeSH], Translational research, Molecular imaging, Neoplasms/metabolism [MeSH], Original Article, Mice [MeSH], Ligands [MeSH], Gallium Radioisotopes [MeSH], Tissue Distribution [MeSH], FAPI, Positron Emission Tomography Computed Tomography/methods [MeSH], Fibroblasts/metabolism [MeSH], Radiosynthesis |
| الوصف: |
Purpose!#!The fibroblast activation protein (FAP) is an emerging target for molecular imaging and therapy in cancer. OncoFAP is a novel small organic ligand for FAP with very high affinity. In this translational study, we establish [!##!Methods!#!68!##!Results!#!68!##!Conclusion!#!Favorable radiochemical properties, rapid clearance from organs and soft tissues, and intense tumor uptake validate |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
https://repository.publisso.de/resource/frl:6451451Test; https://doi.org/10.1007/s00259-021-05653-0Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016025Test/ |
| DOI: |
10.1007/s00259-021-05653-0 |
| الإتاحة: |
https://doi.org/10.1007/s00259-021-05653-0Test
https://repository.publisso.de/resource/frl:6451451Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016025Test/ |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.C6E461FB |
| قاعدة البيانات: |
BASE |
