دورية أكاديمية
The Impact of the Virulence of Pseudomonas aeruginosa Isolated from Dogs
| العنوان: | The Impact of the Virulence of Pseudomonas aeruginosa Isolated from Dogs |
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| المؤلفون: | de Sousa, Telma, Garcês, Andreia, Silva, Augusto, Lopes, Ricardo, Alegria, Nuno, Hébraud, Michel, Igrejas, Gilberto, Poeta, Patricia |
| المساهمون: | Universidade de Trás-os-Montes e Alto Douro (UTAD), Universidade do Trás-os-Montes e Alto Douro, INNO Laboratório Veterinário, Microbiologie Environnement Digestif Santé (MEDIS), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA) |
| المصدر: | ISSN: 2306-7381 ; Veterinary Sciences ; https://hal.inrae.fr/hal-04097313Test ; Veterinary Sciences, 2023, 10 (5), pp.343. ⟨10.3390/vetsci10050343⟩. |
| بيانات النشر: | HAL CCSD MDPI |
| سنة النشر: | 2023 |
| المجموعة: | HAL Clermont Auvergne (Université Blaise Pascal Clermont-Ferrand / Université d'Auvergne) |
| مصطلحات موضوعية: | Pseudomonas aeruginosa, dogs, antibiotic resistance, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Pseudomonas aeruginosa is a pathogenic bacterium that can cause serious infections in both humans and animals, including dogs. Treatment of this bacterium is challenging because some strains have developed multi-drug resistance. This study aimed to evaluate the antimicrobial resistance patterns and biofilm production of clinical isolates of P. aeruginosa obtained from dogs. The study found that resistance to various β-lactam antimicrobials was widespread, with cefovecin and ceftiofur showing resistance in 74% and 59% of the isolates tested, respectively. Among the aminoglycosides, all strains showed susceptibility to amikacin and tobramycin, while gentamicin resistance was observed in 7% of the tested isolates. Furthermore, all isolates carried the oprD gene, which is essential in governing the entry of antibiotics into bacterial cells. The study also investigated the presence of virulence genes and found that all isolates carried exoS, exoA, exoT, exoY, aprA, algD, and plcH genes. This study compared P. aeruginosa resistance patterns worldwide, emphasizing regional understanding and responsible antibiotic use to prevent multi-drug resistance from emerging. In general, the results of this study emphasize the importance of the continued monitoring of antimicrobial resistance in veterinary medicine. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37235426; hal-04097313; https://hal.inrae.fr/hal-04097313Test; https://hal.inrae.fr/hal-04097313/documentTest; https://hal.inrae.fr/hal-04097313/file/DE%20SOUSA_VetSciences_2023.pdfTest; PUBMED: 37235426; WOS: 000997527000001 |
| DOI: | 10.3390/vetsci10050343 |
| الإتاحة: | https://doi.org/10.3390/vetsci10050343Test https://hal.inrae.fr/hal-04097313Test https://hal.inrae.fr/hal-04097313/documentTest https://hal.inrae.fr/hal-04097313/file/DE%20SOUSA_VetSciences_2023.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.C6CEE7D0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/vetsci10050343 |
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