دورية أكاديمية
Determinants of rejection rate for coronary CT angiography fractional flow reserve analysis
| العنوان: | Determinants of rejection rate for coronary CT angiography fractional flow reserve analysis |
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| المؤلفون: | Pontone G., Weir-McCall J. R., Baggiano A., Del Torto A., Fusini L., Guglielmo M., Muscogiuri G., Guaricci A. I., Andreini D., Patel M., Nieman K., Akasaka T., Rogers C., Norgaard B. L., Bax J., Raff G. L., Chinnaiyan K., Berman D., Fairbairn T., Koweek L. H., Leipsic J. |
| المساهمون: | G. Pontone, J.R. Weir-McCall, A. Baggiano, A. Del Torto, L. Fusini, M. Guglielmo, G. Muscogiuri, A.I. Guaricci, D. Andreini, M. Patel, K. Nieman, T. Akasaka, C. Roger, B.L. Norgaard, J. Bax, G.L. Raff, K. Chinnaiyan, D. Berman, T. Fairbairn, L.H. Koweek, J. Leipsic |
| بيانات النشر: | Radiological Society of North America |
| سنة النشر: | 2019 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | Aged, Cohort Studie, Computed Tomography Angiography, Coronary Angiography, Coronary Stenosi, Female, Fractional Flow Reserve, Myocardial, Human, Male, Prospective Studie, Registrie, Reproducibility of Result, Severity of Illness Index, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Settore MED/36 - Diagnostica per Immagini e Radioterapia |
| الوصف: | Background: Coronary artery fractional flow reserve (FFR) derived from CT angiography (FFTCT) enables functional assessment of coronary stenosis. Prior clinical trials showed 13%-33% of coronary CT angiography studies had insufficient quality for quantitative analysis with FFRCT. Purpose: To determine the rejection rate of FFRCT analysis and to determine factors associated with technically unsuccessful calculation of FFRCT. Materials and Methods: Prospectively acquired coronary CT angiography scans submitted as part of the Assessing Diagnostic Value of Noninvasive FFRCT in Coronary Care (ADVANCE) registry (https://ClinicalTrials.govTest: NCT02499679) and coronary CT angiography series submitted for clinical analysis were included. The primary outcome was the FFRCT rejection rate (defined as an inability to perform quantitative analysis with FFRCT). Factors that were associated with FFRCT rejection rate were assessed with multiple linear regression. Results: In the ADVANCE registry, FFRCT rejection rate due to inadequate image quality was 2.9% (80 of 2778 patients; 95% confidence interval [CI]: 2.1%, 3.2%). In the 10 621 consecutive patients who underwent clinical analysis, the FFRCT rejection rate was 8.4% (n = 892; 95% CI: 6.2%, 7.2%; P , .001 vs the ADVANCE cohort). The main reason for the inability to perform FFRCT analysis was the presence of motion artifacts (63 of 80 [78%] and 729 of 892 [64%] in the ADVANCE and clinical cohorts, respectively). At multivariable analysis, section thickness in the ADVANCE (odds ratio [OR], 1.04; 95% CI: 1.001, 1.09; P = .045) and clinical (OR, 1.03; 95% CI: 1.02, 1.04; P , .001) cohorts and heart rate in the ADVANCE (OR, 1.05; 95% CI: 1.02, 1.08; P , .001) and clinical (OR, 1.06; 95% CI: 1.05, 1.07; P , .001) cohorts were independent predictors of rejection. Conclusion: The rates for technically unsuccessful CT-derived fractional flow reserve in the ADVANCE registry and in a large clinical cohort were 2.9% and 8.4%, respectively. Thinner CT section thickness and lower patient ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31335283; info:eu-repo/semantics/altIdentifier/wos/WOS:000482215800016; volume:292; issue:3; firstpage:597; lastpage:605; numberofpages:9; journal:RADIOLOGY; http://hdl.handle.net/2434/721355Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85071387239 |
| DOI: | 10.1148/radiol.2019182673 |
| الإتاحة: | https://doi.org/10.1148/radiol.2019182673Test http://hdl.handle.net/2434/721355Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.C5901F52 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1148/radiol.2019182673 |
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