التفاصيل البيبلوغرافية
| العنوان: |
Reproductive Endocrinologists’ Utilization of Genetic Counselors for Oncofertility and Preimplantation Genetic Diagnosis (PGD) Treatment of BRCA1/2 Mutation Carriers |
| المؤلفون: |
Goetsch, Allison L., Wicklund, Catherine, Clayman, Marla L., Woodruff, Teresa K. |
| المساهمون: |
National Institutes of Health, National Institute of Child Health and Human Development |
| المصدر: |
Journal of Genetic Counseling ; volume 25, issue 3, page 561-571 ; ISSN 1059-7700 1573-3599 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2015 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Genetic counselors believe fertility preservation and preimplantation genetic diagnosis (PGD) discussions to be a part of their role when counseling BRCA1/2 mutation‐positive patients. This study is the first to explore reproductive endocrinologists’ (REI) practices and attitudes regarding involvement of genetic counselors in the care of BRCA1/2 mutation carriers seeking fertility preservation and PGD. A survey was mailed to 1000 REIs from Reproductive Endocrinology & Infertility (SREI), an American Society for Reproductive Medicine (ASRM) affiliate group. A 14.5 % response rate was achieved; data was analyzed using SPSS software. The majority of participating REIs were found to recommend genetic counseling to cancer patients considering fertility preservation (82 %) and consult with a genetic counselor regarding PGD for hereditary cancer syndromes (92 %). Additionally, REIs consult genetic counselors regarding PGD patient counseling (88 %), genetic testing (78 %), and general genetics questions (66 %). Two areas genetic counselors may further aid REIs are: elicitation of family history, which is useful to determine fertility preservation and PGD intervention timing (32 % of REIs utilize a cancer family history to determine intervention timing); and, interpretation of variants of uncertain significance (VOUS) as cancer panel genetic testing becomes more common (36 % of REIs are unfamiliar with VOUS). Given our findings, the Oncofertility Consortium® created an online resource for genetic counselors focused on fertility preservation education and communication strategies. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1007/s10897-015-9908-7 |
| DOI: |
10.1007/s10897-015-9908-7.pdf |
| DOI: |
10.1007/s10897-015-9908-7/fulltext.html |
| الإتاحة: |
https://doi.org/10.1007/s10897-015-9908-7Test |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest ; http://www.springer.com/tdmTest |
| رقم الانضمام: |
edsbas.C49D70D7 |
| قاعدة البيانات: |
BASE |
