دورية أكاديمية
Molecular mechanism of fetal hemoglobin induction by a lead compound isolated from TCM.
| العنوان: | Molecular mechanism of fetal hemoglobin induction by a lead compound isolated from TCM. |
|---|---|
| المساهمون: | Choi, Wai-wah., Chinese University of Hong Kong Graduate School. Division of Molecular Biotechnology. |
| سنة النشر: | 2006 |
| المجموعة: | The Chinese University of Hong Kong: CUHK Digital Repository / 香港中文大學數碼典藏 |
| مصطلحات موضوعية: | Hemoglobin--Synthesis--Regulation, Fetal blood, Globin genes, Genetic regulation, Lead compounds, Medicine, Chinese, Fetal Hemoglobin--biosynthesis, Fetal Hemoglobin--genetics, Globins--genetics, Lead, Gene Expression Regulation, Drugs, Chinese Herbal |
| الوصف: | Choi Wai-wah. ; Thesis (M.Phil.)--Chinese University of Hong Kong, 2006. ; Includes bibliographical references (leaves 120-138). ; Abstracts in English and Chinese. ; Statement --- p.i ; Acknowledgements --- p.ii ; Abstract --- p.iii ; Abstract (Chinese Version) --- p.v ; Table of Contents --- p.vii ; List of Tables --- p.xii ; List of Figures --- p.xiii ; List of Abbreviations --- p.xv ; Chapter Chapter 1 --- General Introduction ; Chapter 1.1 --- "Hemoglobin ´ؤ Structures, Types and Functions" --- p.1 ; Chapter 1.1.1 --- Structures of Hemoglobin --- p.1 ; Chapter 1.1.2 --- Types of Hemoglobin --- p.2 ; Chapter 1.1.3 --- Functions of Hemoglobin --- p.3 ; Chapter 1.2 --- Human Globin Genes and Their Regulation --- p.5 ; Chapter 1.2.1 --- Organization of the Human Globin Genes --- p.5 ; Chapter 1.2.2 --- Regulation of Globin Gene Expression --- p.6 ; Chapter 1.2.2.1 --- The Locus Control Region (LCR) --- p.6 ; Chapter 1.2.2.2 --- Cis-Regulatory Elements --- p.7 ; Chapter 1.2.2.2.1 --- Promoters --- p.7 ; Chapter 1.2.2.2.2 --- Enhancers --- p.7 ; Chapter 1.2.2.2.3 --- Silencers --- p.8 ; Chapter 1.2.2.3 --- Trans-Acting Factors --- p.8 ; Chapter 1.2.2.3.1 --- GATA Family --- p.9 ; Chapter 1.2.2.3.2 --- Kruppel-like Factors --- p.9 ; Chapter 1.2.2.3.3 --- Nuclear Factor-Erythroid (NF-E) --- p.9 ; Chapter 1.2.2.4 --- Chromatin Remodelling --- p.10 ; Chapter 1.2.2.5 --- Intergenic Sequences --- p.11 ; Chapter 1.3 --- Mechanisms of Hemoglobin Switching --- p.12 ; Chapter 1.3.1 --- Autonomous Silencing --- p.12 ; Chapter 1.3.2 --- LCR and Globin Gene Interaction --- p.12 ; Chapter 1.4 --- Hemoglobinopathies --- p.14 ; Chapter 1.4.1 --- α -thalassemia --- p.14 ; Chapter 1.4.2 --- β -thalassemia --- p.14 ; Chapter 1.4.3 --- Sickle Cell Anemia --- p.16 ; Chapter 1.5 --- Therapies for β-thalassemia --- p.16 ; Chapter 1.5.1 --- Blood Transfusion --- p.16 ; Chapter 1.5.2 --- Bone Marrow Transplantation --- p.17 ; Chapter 1.5.3. --- Gene Therapy --- p.17 ; Chapter 1.6 --- Gene Switch Therapy --- p.18 ; Chapter "1.6,1" --- ... |
| نوع الوثيقة: | text |
| وصف الملف: | print; xvi, 138 leaves : ill. (some col.); 30 cm. |
| اللغة: | English Chinese |
| العلاقة: | cuhk:325694; http://library.cuhk.edu.hk/record=b5896527Test; https://repository.lib.cuhk.edu.hk/en/item/cuhk-325694Test |
| الإتاحة: | http://library.cuhk.edu.hk/record=b5896527Test https://repository.lib.cuhk.edu.hk/en/item/cuhk-325694Test |
| حقوق: | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0Test/) |
| رقم الانضمام: | edsbas.C3B295AF |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |