دورية أكاديمية

Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo

التفاصيل البيبلوغرافية
العنوان: Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo
المؤلفون: Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen
المساهمون: Cancer Research UK, Sixth Element Capital
المصدر: Journal of Medicinal Chemistry ; volume 65, issue 12, page 8191-8207 ; ISSN 0022-2623 1520-4804
بيانات النشر: American Chemical Society (ACS)
سنة النشر: 2022
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1021/acs.jmedchem.1c02175
الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c02175Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.C2AFDF3E
قاعدة البيانات: BASE