دورية أكاديمية
Assessment of Insulin Secretion and Insulin Resistance in Human
| العنوان: | Assessment of Insulin Secretion and Insulin Resistance in Human |
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| المؤلفون: | So Young Park, Jean-François Gautier, Suk Chon |
| المصدر: | Diabetes & Metabolism Journal, Vol 45, Iss 5, Pp 641-654 (2021) |
| بيانات النشر: | Korean Diabetes Association |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | diabetes mellitus, insulin resistance, insulin secretion, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | The impaired insulin secretion and increased insulin resistance (or decreased insulin sensitivity) play a major role in the pathogenesis of all types of diabetes mellitus (DM). It is very important to assess the pancreatic β-cell function and insulin resistance/sensitivity to determine the type of DM and to plan an optimal management and prevention strategy for DM. So far, various methods and indices have been developed to assess the β-cell function and insulin resistance/sensitivity based on static, dynamic test and calculation of their results. In fact, since the metabolism of glucose and insulin is made through a complex process related with various stimuli in several tissues, it is difficult to fully reflect the real physiology. In order to solve the theoretical and practical difficulties, research on new index is still in progress. Also, it is important to select the appropriate method and index for the purpose of use and clinical situation. This review summarized a variety of traditional methods and indices to evaluate pancreatic β-cell function and insulin resistance/sensitivity and introduced novel indices. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2233-6079 2233-6087 |
| العلاقة: | http://www.e-dmj.org/upload/pdf/dmj-2021-0220.pdfTest; https://doaj.org/toc/2233-6079Test; https://doaj.org/toc/2233-6087Test; https://doaj.org/article/19803de44e054ac382eba408a99f0361Test |
| DOI: | 10.4093/dmj.2021.0220 |
| الإتاحة: | https://doi.org/10.4093/dmj.2021.0220Test https://doaj.org/article/19803de44e054ac382eba408a99f0361Test |
| رقم الانضمام: | edsbas.C213CC37 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 22336079 22336087 |
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| DOI: | 10.4093/dmj.2021.0220 |