دورية أكاديمية
Treatment with direct-acting antivirals improves peripheral insulin sensitivity in non-diabetic, lean chronic hepatitis c patients
| العنوان: | Treatment with direct-acting antivirals improves peripheral insulin sensitivity in non-diabetic, lean chronic hepatitis c patients |
|---|---|
| المؤلفون: | Gastaldi, Giacomo Gianni Giuseppe, Rocha Gomes, Diana Bianca, Schneiter, Philippe, Montet, Xavier Cédric Rodolphe, Tappy, Luc, Clement, Sophie, Negro, Francesco |
| المصدر: | ISSN: 1932-6203 ; PLOS ONE, vol. 14, no. 6 (2019) e0217751. |
| سنة النشر: | 2019 |
| المجموعة: | Université de Genève: Archive ouverte UNIGE |
| مصطلحات موضوعية: | info:eu-repo/classification/ddc/616, info:eu-repo/classification/ddc/616.07, info:eu-repo/classification/ddc/616.0757, Adenine Nucleotides/pharmacology, Animals, Biological Transport/drug effects, Cyclic AMP/metabolism, Cyclooxygenase Inhibitors, Lymphocyte Activation, Lymphocytes/immunology/metabolism, Phytohemagglutinins/pharmacology, Prostaglandins E/metabolism, Swine, Uridine/metabolism |
| الوصف: | Hepatitis C virus (HCV) infection is associated with insulin resistance, which may lead to type 2 diabetes and its complications. Although HCV infects mainly hepatocytes, it may impair insulin sensitivity at the level of uninfected extrahepatic tissues (muscles and adipose tissue). The aim of this study was to assess whether an interferon-free, antiviral therapy may improve HCV-associated hepatic vs. peripheral insulin sensitivity. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31170218; https://archive-ouverte.unige.ch/unige:123540Test; unige:123540 |
| الإتاحة: | https://doi.org/10.1371/journal.pone.0217751Test https://archive-ouverte.unige.ch/unige:123540Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.C0F2DEF8 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |