دورية أكاديمية
Synthesis, spectroscopy and structural elucidation of two new CoII and NiII complexes of pyrazole derived heterocyclic Schiff base ligand as potential anticancer and photocatalytic agents
| العنوان: | Synthesis, spectroscopy and structural elucidation of two new CoII and NiII complexes of pyrazole derived heterocyclic Schiff base ligand as potential anticancer and photocatalytic agents |
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| المؤلفون: | Mandal, Suman, Bagchi, Arka, Biswas, Arunima, Cordes, David B., Slawin, Alexandra M. Z., Saha, Nitis Chandra |
| المساهمون: | University of St Andrews. School of Chemistry, University of St Andrews. EaSTCHEM |
| سنة النشر: | 2024 |
| المجموعة: | University of St Andrews: Digital Research Repository |
| مصطلحات موضوعية: | CoII and NiII complexes, Crystal structures, π…π stacking, Anticancer activity, Photocatalytic activity, QD Chemistry, 3rd-DAS, QD |
| الوصف: | Dr. Arunima Biswas has received research grant from West Bengal DBT, vide grant no. (676/(Sanc.)/BT/(Estt.)/RD27/2016). ; Two new complexes I and II of general composition, [ML3]X2.nH2O (where, M = CoII and NiII for I and II, respectively, L = MPAFA, X = Br and n = 2) were synthesized from a pyrazolyl Schiff base ligand, MPAFA (L). I and II were characterised through several physico-chemical and spectroscopic techniques, viz., C, H, N analyses, estimation of metal contents, conductance and magnetic susceptibility measurements, IR, electronic and fluorescence spectral studies. Both the reported coordination complexes were cationic in nature and behaved as 1:2 electrolytes. According to IR spectra, each of the MPAFA molecule coordinated to the metal centres via the azomethine nitrogen and the pyrazolyl tertiary nitrogen atoms. Single crystal X-ray diffraction studies of I and II had established a N6 donor set with a distorted octahedral structure for both the cases. Both the complexes exhibited some non-covalent interactions, like π…π stacking, H-bonding contacts etc. L, I and II had also been found to possess fluorescence property. Anticancer activities of L, I and II had been investigated and it was found that both the complexes I and II were stronger cytotoxic agents against the breast cancer cell line MCF7 than the primary ligand system; while all of them (L, I and II) were less toxic against a non-cancerous cell line HEK293. All the compounds had shown potential photocatalytic activity in degrading methylene-blue (MB). ; Peer reviewed |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2522-5766 |
| العلاقة: | Chemistry Africa; 299399693; 4f137349-d9db-4d14-9727-88aceba3fc66; 85178885942; Mandal , S , Bagchi , A , Biswas , A , Cordes , D B , Slawin , A M Z & Saha , N C 2023 , ' Synthesis, spectroscopy and structural elucidation of two new Co II and Ni II complexes of pyrazole derived heterocyclic Schiff base ligand as potential anticancer and photocatalytic agents ' , Chemistry Africa , vol. First Online . https://doi.org/10.1007/s42250-023-00827-9Test; ORCID: /0000-0002-9527-6418/work/153977254; ORCID: /0000-0002-5366-9168/work/153977363; https://hdl.handle.net/10023/29299Test |
| DOI: | 10.1007/s42250-023-00827-9 |
| الإتاحة: | https://doi.org/10.1007/s42250-023-00827-9Test https://hdl.handle.net/10023/29299Test |
| رقم الانضمام: | edsbas.C0B32DA8 |
| قاعدة البيانات: | BASE |
| تدمد: | 25225766 |
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| DOI: | 10.1007/s42250-023-00827-9 |