Supplementary information files for The effect of COVID rehabilitation for ongoing symptoms post hospitalisation with COVID-19 (PHOSP-R): protocol for a randomised parallel group controlled trial on behalf of the PHOSP consortium

التفاصيل البيبلوغرافية
العنوان: Supplementary information files for The effect of COVID rehabilitation for ongoing symptoms post hospitalisation with COVID-19 (PHOSP-R): protocol for a randomised parallel group controlled trial on behalf of the PHOSP consortium
المؤلفون: Enya Daynes, Molly Baldwin, Neil J. Greening, Thomas Yates, Nicolette Bishop, George Mills, Matthew Roberts, Malik Hamrouni, Tatiana Plekhanova, Ioannis Vogiatzis, Carlos Echevarria, Rashmita Nathu, Hamish J. C. McAuley, Lorna Latimer, Jennifer Glennie, Francesca Chambers, Ruth Penfold, Emily Hume, Dimitrios Megaritis, Charikleia Alexiou, Sebastian Potthoff, Mitchell James Hogg, Catherine Haighton, Bethany Nichol, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Claire M. Nolan, Charlotte Bolton, Linzy Houchen-Wolloff, Ewen M. Harrison, Nazir Lone, Jennifer Quint, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Ramen, Louise V. Wain, Christopher Brightling, William D.-C. Man, Rachael Evans, Sally J. Singh
سنة النشر: 2023
المجموعة: Loughborough University: Figshare
مصطلحات موضوعية: Cardiovascular medicine and haematology, Clinical sciences, Cardiovascular System & Hematology, General & Internal Medicine, COVID-19, Rehabilitation, Digital Randomised controlled trial
الوصف: Supplementary files for article The effect of COVID rehabilitation for ongoing symptoms post hospitalisation with COVID-19 (PHOSP-R): protocol for a randomised parallel group controlled trial on behalf of the PHOSP consortium Introduction: Many adults hospitalised with COVID-19 have persistent symptoms such as fatigue, breathlessness and brain fog that limit day-to-day activities. These symptoms can last over 2 years. Whilst there is limited controlled studies on interventions that can support those with ongoing symptoms, there has been some promise in rehabilitation interventions in improving function and symptoms either using face-to-face or digital methods, but evidence remains limited and these studies often lack a control group. Methods and analysis: This is a nested single-blind, parallel group, randomised control trial with embedded qualitative evaluation comparing rehabilitation (face-to-face or digital) to usual care and conducted within the PHOSP-COVID study. The aim of this study is to determine the effectiveness of rehabilitation interventions on exercise capacity, quality of life and symptoms such as breathlessness and fatigue. The primary outcome is the Incremental Shuttle Walking Test following the eight week intervention phase. Secondary outcomes include measures of function, strength and subjective assessment of symptoms. Blood inflammatory markers and muscle biopsies are an exploratory outcome. The interventions last eight weeks and combine symptom-titrated exercise therapy, symptom management and education delivered either in a face-to-face setting or through a digital platform (www.yourcovidrecovery.nhs.uk). The proposed sample size is 159 participants, and data will be intention-to-treat analyses comparing rehabilitation (face-to-face or digital) to usual care. Ethics and dissemination: Ethical approval was gained as part of the PHOSP-COVID study by Yorkshire and the Humber Leeds West Research NHS Ethics Committee, and the study was prospectively registered on the ISRCTN trial registry ...
نوع الوثيقة: dataset
اللغة: unknown
العلاقة: https://figshare.com/articles/dataset/Supplementary_information_files_for_The_effect_of_COVID_rehabilitation_for_ongoing_symptoms_post_hospitalisation_with_COVID-19_PHOSP-R_protocol_for_a_randomised_parallel_group_controlled_trial_on_behalf_of_the_PHOSP_consortium/22189279Test
DOI: 10.17028/rd.lboro.22189279.v1
الإتاحة: https://doi.org/10.17028/rd.lboro.22189279.v1Test
https://figshare.com/articles/dataset/Supplementary_information_files_for_The_effect_of_COVID_rehabilitation_for_ongoing_symptoms_post_hospitalisation_with_COVID-19_PHOSP-R_protocol_for_a_randomised_parallel_group_controlled_trial_on_behalf_of_the_PHOSP_consortium/22189279Test
حقوق: CC BY 4.0
رقم الانضمام: edsbas.C06EB012
قاعدة البيانات: BASE