دورية أكاديمية
Terminal Weaning or Immediate Extubation for Withdrawing Mechanical Ventilation in Critically Ill Patients (the ARREVE Observational Study)
| العنوان: | Terminal Weaning or Immediate Extubation for Withdrawing Mechanical Ventilation in Critically Ill Patients (the ARREVE Observational Study) |
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| المؤلفون: | Robert, René, Le Gouge, Amélie, Kentish-Barnes, Nancy, Cottereau, Alice, Giraudeau, Bruno, Adda, Mélanie, Annane, Djillali, Audibert, Juliette, Barbier, François, Bardou, Patrick, Bourcier, Simon, Bourenne, Jeremy, Boyer, Alexandre, Brenas, François, Das, Vincent, Desachy, Arnaud, Devaquet, Jérôme, Feissel, Marc, Ganster, Frédérique, Garrouste-Orgeas, Maïté, Grillet, Guillaume, Guisset, Olivier, Hamidfar-Roy, Rebecca, Hyacinthe, Anne-Claire, Jochmans, Sebastien, Jourdain, Mercé, Lautrette, Alexandre, Lerolle, Nicolas, Lesieur, Olivier, Lion, Fabien, Mateu, Philippe, Mégarbane, Bruno, Merceron, Sybille, Mercier, Emmanuelle, Messika, Jonathan, Morin-Longuet, Paul, Philippon-Jouve, Bénédicte, Quenot, Jean-Pierre, Renault, Anne, Repesse, Xavier, Rigaud, Jean-Philippe, Robin, Ségolène, Roquilly, Antoine, Seguin, Amélie, Thevenin, Didier, Tirot, Patrice, Vinatier, Isabelle, Azoulay, Elie, Reignier, Jean |
| المساهمون: | MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN) |
| المصدر: | ISSN: 0342-4642. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2017 |
| المجموعة: | Université François-Rabelais de Tours: HAL |
| مصطلحات موضوعية: | Airway Extubation, Anxiety, Chi-Square Distribution, Critical care, Critical Illness, Depression, Ethics, Family, Female, Grief, Humans, Immediate extubation, Intensive Care Units, Length of Stay, Male, Mechanical ventilation, Middle Aged, Personnel, Hospital, Prospective Studies, Stress Disorders, Post-Traumatic, Terminal weaning, Time Factors, Treatment limitation, Ventilator Weaning, Adult, Aged, 80 and over, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; PURPOSE: The relative merits of immediate extubation versus terminal weaning for mechanical ventilation withdrawal are controversial, particularly regarding the experience of patients and relatives. METHODS: This prospective observational multicentre study (ARREVE) was done in 43 French ICUs to compare terminal weaning and immediate extubation, as chosen by the ICU team. Terminal weaning was a gradual decrease in the amount of ventilatory assistance and immediate extubation was extubation without any previous decrease in ventilatory assistance. The primary outcome was posttraumatic stress symptoms (Impact of Event Scale Revised, IES-R) in relatives 3~months after the death. Secondary outcomes were complicated grief, anxiety, and depression symptoms in relatives; comfort of patients during the dying process; and job strain in staff. RESULTS: We enrolled 212 (85.5%) relatives of 248 patients with terminal weaning and 190 relatives (90.5%) of 210 patients with immediate extubation. Immediate extubation was associated with airway obstruction and a higher mean Behavioural Pain Scale score compared to terminal weaning. In relatives, IES-R scores after 3~months were not significantly different between groups (31.9~±~18.1 versus 30.5~±~16.2, respectively; adjusted difference, -1.9; 95% confidence interval, -5.9 to 2.1; p~=~0.36); neither were there any differences in complicated grief, anxiety, or depression scores. Assistant nurses had lower job strain scores in the immediate extubation group. CONCLUSIONS: Compared to terminal weaning, immediate extubation was not associated with differences in psychological welfare of relatives when each method constituted standard practice in the ICU where it was applied. Patients had more airway obstruction and gasps with immediate extubation. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01818895. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-03158151; https://hal.science/hal-03158151Test |
| DOI: | 10.1007/s00134-017-4891-0 |
| الإتاحة: | https://doi.org/10.1007/s00134-017-4891-0Test https://hal.science/hal-03158151Test |
| رقم الانضمام: | edsbas.C02958CC |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00134-017-4891-0 |
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