التفاصيل البيبلوغرافية
| العنوان: |
Prognostic value of C‐reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy |
| المؤلفون: |
Kuboki, Akihito, Kanaya, Hiroaki, Nakayama, Tsuguhisa, Konno, Wataru, Goto, Kazutaka, Nakajima, Itsuo, Kashiwagi, Takashi, Hirabayashi, Hideki, Haruna, Shin‐ichi |
| المصدر: |
Head & Neck ; volume 41, issue 5, page 1342-1350 ; ISSN 1043-3074 1097-0347 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2018 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Background The C‐reactive protein/albumin (CRP/Alb) ratio has been recently established as a prognostic indicator in various cancer types. However, few reports regarding the prognostic value of the CRP/Alb ratio in head and neck cancer exist. This study aimed to investigate the significance of the CRP/Alb ratio in clinical outcomes after invasive surgery involving laryngectomy for hypopharyngeal and laryngeal cancer. Methods We evaluated 56 patients who underwent total laryngectomy or total pharyngolaryngectomy between 2003 and 2012. Univariate and multivariate analyses were retrospectively performed to examine the prognostic value of the CRP/Alb ratio in these patients. Results The optimal cutoff value of the CRP/Alb ratio was 0.32. Multivariate analysis showed that the CRP/Alb ratio was a significant and independent predictor of poor overall and disease‐free survival. Conclusion The CRP/Alb ratio may be a novel and useful indicator for predicting postoperative outcomes in patients with hypopharyngeal and laryngeal cancer. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1002/hed.25565 |
| الإتاحة: |
https://doi.org/10.1002/hed.25565Test |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.BFB3BD0E |
| قاعدة البيانات: |
BASE |
