دورية أكاديمية
Release of VEGF from dental implant surface (IML® implant) coated with Concentrated Growth Factors (CGF) and the liquid phase of CGF (LPCGF): In vitro results and future expectations
| العنوان: | Release of VEGF from dental implant surface (IML® implant) coated with Concentrated Growth Factors (CGF) and the liquid phase of CGF (LPCGF): In vitro results and future expectations |
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| المؤلفون: | Palermo A., Ferrante F., Stanca E., Damiano F., GNONI, ANTONIO, Batani T., Carluccio M. A., Demitri C., Siculella L. |
| المساهمون: | Palermo, A., Ferrante, F., Stanca, E., Damiano, F., Gnoni, Antonio, Batani, T., Carluccio, M. A., Demitri, C., Siculella, L. |
| سنة النشر: | 2019 |
| المجموعة: | Università degli Studi di Bari Aldo Moro: CINECA IRIS |
| مصطلحات موضوعية: | Bilateral osseointegration, Dental implant, Growth factor |
| الوصف: | This study aimed to evaluate the combined use of the Concentrated Growth Factor (CGF) and the liquid phase of CGF (LPCGF) on dental implant surfaces, using a medical device to determine the migration of growth factors, from the implant surface to the recipient. The implants were permeated by autologous growth factors, using a specific centrifuge device. CGF adhesion on the implant surface was evaluated through a scanning electron microscope analysis. To assess the release of the vascular endothelial growth factor (VEGF) from CGF, LPCGF, and CGF- or LPCGF-permeated implant, an ELISA assay was carried out. The results showed that the concentration of the growth factor VEGF was greater in CGF than in LPCGF. Our innovative technique allowed the incorporation of autologous growth factors on the surface of the dental implants. Moreover, we reported the release of VEGF, over time, by CGF- or LPCGF-permeated implant. On this basis, it was possible to obtain a biologically active implant surface, essential to create intercellular communication and neo-angiogenesis, to facilitate wound healing and tissue regeneration. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000473748100149; volume:9; issue:10; firstpage:2114; numberofpages:8; journal:APPLIED SCIENCES; http://hdl.handle.net/11586/236410Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85066482343; https://res.mdpi.com/applsci/applsci-09-02114/article_deploy/applsci-09-02114-v2.pdf?filename=&attachment=1Test |
| DOI: | 10.3390/app9102114 |
| الإتاحة: | https://doi.org/10.3390/app9102114Test http://hdl.handle.net/11586/236410Test https://res.mdpi.com/applsci/applsci-09-02114/article_deploy/applsci-09-02114-v2.pdf?filename=&attachment=1Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.BF3388D8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/app9102114 |
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