دورية أكاديمية
Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic : a cross-sectional study
| العنوان: | Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic : a cross-sectional study |
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| المؤلفون: | Htun, Nan Shwe Nwe, Odermatt, Peter, Paboriboune, Phimpha, Sayasone, Somphou, Vongsakid, Malisa, Phimolsarn-Nusith, Vilayouth, Tran, Xuan Duong, Ounnavong, Phoum-Savath, Andriama-Hefasoa, Navalone, Senvanpan, Nilun-Done, Homsana, Anousine, Lianosay, Baocher, Xayavong, Dalouny, Robinson, Dimbitsoa Rakotomalala, Bounsavath, Phaivanh, Prasayasith, Phoy-Phaylinh, Syphan, Seng-Davanh, Lu, Yi-Xiao, Thilakoun, Kanchana, Xaiyaphet, Xaipa-Song, Vongngakesone, Phout-Tasin, Eze, Ikenna C., Imboden, Medea, Sripa, Banchob, Reinharz, Daniel, Probst-Hensch, Nicole |
| بيانات النشر: | Biomed Central |
| سنة النشر: | 2018 |
| المجموعة: | University of Basel: edoc |
| الوصف: | As a result of epidemiological transition, the health systems of low- and middle-income countries are increasingly faced with a dual disease burden of infectious diseases and emerging non-communicable diseases. Little is known about the mutual influence of these two disease groups. The aim of this study was to investigate the co-occurrence of helminth infections and diabetes mellitus in adults in Lao People's Democratic Republic (Lao PDR).; We conducted a cross-sectional study among 1600 randomly selected adults aged 35 and older from four different socio-economical and ecological provinces. Information on socio-demographics, risk factors and health conditions was obtained from personal interviews. Clinical assessments including anthropometry (height, weight, waist and hip circumference) and blood pressure measurements were also conducted. Diabetes was classified based on self-reported diagnoses and a point-of-care glycated haemoglobin (HbA1c) test from finger prick blood samples. Stool samples for helminth diagnosis were examined with formalin-ether concentration technique for intestinal parasitic infections. The independent associations of helminth infections with diabetic status and HbA1c were assessed using multiple regression analyses.; The prevalence of pre-diabetes and diabetes was 37.3% and 22.8%, respectively. Fifty-six percent of diabetic cases were undiagnosed and 85% of diagnosed diabetic cases had poor glycemic control. Participants from rural areas and from southern parts of the country had higher infection rates, with Opisthorchis viverrini, being the most common helminth infection (30.5%). We found a positive association between Taenia spp. infections and HbA1c (β = 0.117; 95% CI: 0.042-0.200) and diabetes mellitus risk (OR = 2.98; 95% CI: 1.10-8.05). No other helminth species was associated with glycated hemoglobin.; Hyperglycaemia and diabetic rates in Lao PDR are alarmingly high, but consistent with other high rates in the region. Given the high rates of under-diagnosis and poorly-controlled ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2049-9957 |
| العلاقة: | https://edoc.unibas.ch/66808/1/20181115110425_5bed44a90515f.pdfTest; Htun, Nan Shwe Nwe and Odermatt, Peter and Paboriboune, Phimpha and Sayasone, Somphou and Vongsakid, Malisa and Phimolsarn-Nusith, Vilayouth and Tran, Xuan Duong and Ounnavong, Phoum-Savath and Andriama-Hefasoa, Navalone and Senvanpan, Nilun-Done and Homsana, Anousine and Lianosay, Baocher and Xayavong, Dalouny and Robinson, Dimbitsoa Rakotomalala and Bounsavath, Phaivanh and Prasayasith, Phoy-Phaylinh and Syphan, Seng-Davanh and Lu, Yi-Xiao and Thilakoun, Kanchana and Xaiyaphet, Xaipa-Song and Vongngakesone, Phout-Tasin and Eze, Ikenna C. and Imboden, Medea and Sripa, Banchob and Reinharz, Daniel and Probst-Hensch, Nicole. (2018) Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic : a cross-sectional study. Infectious Diseases of Poverty, 7. p. 105.; info:pmid/30396368; urn:ISSN:2049-9957 |
| DOI: | 10.1186/s40249-018-0488-2 |
| الإتاحة: | https://doi.org/10.1186/s40249-018-0488-2Test https://edoc.unibas.ch/66808Test/ https://edoc.unibas.ch/66808/1/20181115110425_5bed44a90515f.pdfTest |
| حقوق: | cc_by ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.BEB286DC |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20499957 |
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| DOI: | 10.1186/s40249-018-0488-2 |