دورية أكاديمية
Immune cell regulation of glia during CNS injury and disease
| العنوان: | Immune cell regulation of glia during CNS injury and disease |
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| المؤلفون: | Greenhalgh, Andrew D., David, Sam, Bennett, F. Chris |
| المساهمون: | Nutrition et Neurobiologie intégrée (NutriNeuro), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Ecole nationale supérieure de chimie, biologie et physique-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), McGill University = Université McGill Montréal, Canada, University of Pennsylvania, Children’s Hospital of Philadelphia (CHOP ), Perelman School of Medicine, University of Pennsylvania Philadelphia |
| المصدر: | ISSN: 1471-0048. |
| بيانات النشر: | HAL CCSD Nature Publishing Group |
| سنة النشر: | 2020 |
| المجموعة: | Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
| مصطلحات موضوعية: | [SDV]Life Sciences [q-bio], [SDV.GEN]Life Sciences [q-bio]/Genetics, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics |
| الوصف: | International audience ; Glial cells are abundant in the CNS and are essential for brain development and homeostasis. These cells also regulate tissue recovery after injury and their dysfunction is a possible contributing factor to neurodegenerative and psychiatric disease. Recent evidence suggests that microglia, which are also the brain's major resident immune cells, provide disease-modifying regulation of the other major glial populations, namely astrocytes and oligodendrocytes. In addition, peripheral immune cells entering the CNS after injury and in disease may directly affect microglial, astrocyte and oligodendrocyte function, suggesting an integrated network of immune cell-glial cell communication. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/32042145; hal-02623233; https://hal.inrae.fr/hal-02623233Test; PRODINRA: 495873; WOS: 000512527300003; PUBMED: 32042145 |
| DOI: | 10.1038/s41583-020-0263-9 |
| الإتاحة: | https://doi.org/10.1038/s41583-020-0263-9Test https://hal.inrae.fr/hal-02623233Test |
| رقم الانضمام: | edsbas.BE8D0380 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41583-020-0263-9 |
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