التفاصيل البيبلوغرافية
| العنوان: |
Adult motor phenotype differentiates Dravet syndrome from Lennox‐Gastaut syndrome and links SCN1A to early onset parkinsonian features |
| المؤلفون: |
Aljaafari, Danah, Fasano, Alfonso, Nascimento, Fábio A., Lang, Anthony E., Andrade, Danielle M. |
| المساهمون: |
Ontario Brain Institute |
| المصدر: |
Epilepsia ; volume 58, issue 3 ; ISSN 0013-9580 1528-1167 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2017 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Summary Distinguishing adult patients with Lennox‐Gastaut syndrome from those with Dravet syndrome is challenging. We have previously reported that patients with Dravet syndrome present a very peculiar motor phenotype. Here we sought to confirm that this association was not linked to the chronic use of antiepileptic drugs or the many lifetime seizures. To this aim, we studied 14 adult patients with Lennox‐Gastaut syndrome and 14 adults with Dravet syndrome because both conditions share similar seizure severity. We found that antecollis and parkinsonian gait were significantly more common in the Dravet group, thus suggesting that these features are part of the Dravet syndrome adult phenotype. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/epi.13692 |
| الإتاحة: |
https://doi.org/10.1111/epi.13692Test |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.BDD0E504 |
| قاعدة البيانات: |
BASE |
