دورية أكاديمية
Microbiological assessment of success and failure in pulp revitalization : a randomized clinical trial using calcium hydroxide and chlorhexidine gluconate in traumatized immature necrotic teeth
| العنوان: | Microbiological assessment of success and failure in pulp revitalization : a randomized clinical trial using calcium hydroxide and chlorhexidine gluconate in traumatized immature necrotic teeth |
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| المؤلفون: | Wikström, Alina, Romani Vestman, Nelly, Rakhimova, Olena, Lazaro Gimeno, David, Tsilingaridis, Georgios, Brundin, Malin |
| بيانات النشر: | UmeÃ¥ universitet, Institutionen för odontologi UmeÃ¥ universitet, Wallenberg centrum för molekylär medicin vid UmeÃ¥ universitet (WCMM) UmeÃ¥ universitet, Institutionen för fysiologisk botanik UmeÃ¥ universitet, UmeÃ¥ Plant Science Centre (UPSC) Division of Orthodontics and Paediatric Dentistry, Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden; Department of Endodontics, Public Dental Health Services, Stockholm, Eastmaninstitutet, Sweden; Centre of Paediatric Oral Health, Huddinge, Sweden Division of Orthodontics and Paediatric Dentistry, Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden; Centre of Paediatric Oral Health, Huddinge, Sweden |
| سنة النشر: | 2024 |
| المجموعة: | Umeå University: Publications (DiVA) |
| مصطلحات موضوعية: | calcium hydroxide, chlorhexidine gluconate, dental trauma, endodontic pulp revitalization, immature traumatized necrotic teeth, microbiological assessment, Dentistry, Odontologi |
| الوصف: | Aim: To compare differences in the disinfection efficacy of calcium hydroxide (CH) and chlorhexidine gluconate (CHD) dressings in pulp revitalization (PR) of traumatized immature necrotic teeth; to investigate the microflora in successful/failed PR and whether bacterial persistence influences the outcomes of PR. Methods: Microbiological assessment of the average bacterial load (CFU/sample) and bacterial diversity (taxa/sample) was performed on 41 teeth at three timepoints (S2-before, S3-after debridement and S5- after root canal dressing). Results: The primary microflora was more diverse in successful cases than in failed. Decreases in CFU/sample and taxa/sample occurred S2 - S3, though new increases occurred at S5 in the CHD subgroup (successful and failed) and CFU/sample in the CH subgroup (failed). At S5, the successful cases showed more bacterial decreases. No specific species was associated with the outcomes with no statistical differences between the disinfection efficacy. Conclusions: There were no statistical differences in CH and CHD efficacy. At S5, microflora persisted in both successful and failed outcomes, but the abundance and diversity increased significantly only in the failed cases. The successful outcomes presented higher diversity and higher decreases of the primary microflora at S5 than the failed outcomes. The abundance and diversity increased significantly at S5 only in failed cases. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Journal of Oral Microbiology, 2024, 16:1; orcid:0000-0002-5674-8179; orcid:0000-0002-3536-4467; orcid:0000-0002-8747-3307; http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-223944Test; PMID 38665416; ISI:001207663700001; Scopus 2-s2.0-85191169436 |
| DOI: | 10.1080/20002297.2024.2343518 |
| الإتاحة: | https://doi.org/10.1080/20002297.2024.2343518Test http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-223944Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.BC1090A9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1080/20002297.2024.2343518 |
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