دورية أكاديمية
Raltegravir in second-line antiretroviral therapy in resource-limited settings (SELECT): a randomised, phase 3, non-inferiority study
| العنوان: | Raltegravir in second-line antiretroviral therapy in resource-limited settings (SELECT): a randomised, phase 3, non-inferiority study |
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| المؤلفون: | La Rosa, Alberto M, Harrison, Linda J, Taiwo, Babafemi, Wallis, Carole L, Zheng, Lu, Kim, Peter, Kumarasamy, Nagalingeswaran, Hosseinipour, Mina C, Jarocki, Bernadette, Mellors, John W, Collier, Ann C |
| المصدر: | The Lancet HIV, 3(6) |
| سنة النشر: | 2016 |
| المجموعة: | Carolina Digital Repository (UNC - University of North Carolina) |
| مصطلحات موضوعية: | Health Services Accessibility, Africa South of the Sahara, Adult, CD4 Lymphocyte Count, India, Brazil, Drug Resistance, Viral, HIV Infections, Anti-HIV Agents, Humans, Health Resources, Antiretroviral Therapy, Highly Active, HIV-1 |
| الوصف: | For second-line antiretroviral therapy, WHO recommends a boosted protease inhibitor plus nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs). However, concerns about toxicity and cross-resistance motivated a search for regimens that do not contain NRTIs. We aimed to assess whether boosted lopinavir plus raltegravir would be non-inferior to boosted lopinavir plus NRTIs for virological suppression in resource-limited settings. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.17615/r2ze-yy37Test; https://cdr.lib.unc.edu/downloads/rn301647p?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/rn301647pTest |
| DOI: | 10.17615/r2ze-yy37 |
| الإتاحة: | https://doi.org/10.17615/r2ze-yy37Test https://cdr.lib.unc.edu/downloads/rn301647p?file=thumbnailTest https://cdr.lib.unc.edu/downloads/rn301647pTest |
| حقوق: | http://rightsstatements.org/vocab/InC/1.0Test/ |
| رقم الانضمام: | edsbas.BBB37C3E |
| قاعدة البيانات: | BASE |
| DOI: | 10.17615/r2ze-yy37 |
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