دورية أكاديمية
Relationship Between Cerebrovascular Reactivity and Depression in Patients With End-Stage Renal Disease.
| العنوان: | Relationship Between Cerebrovascular Reactivity and Depression in Patients With End-Stage Renal Disease. |
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| المؤلفون: | Li, Shu-Ying, Chen, Rui, Tang, Wei-Ting, Ma, Xiao-Jie, Cai, Hua-Bin, You, Yong |
| المصدر: | Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; ISSN:1000-503X |
| بيانات النشر: | Chinese Academy of Medical Sciences |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | anxiety, cerebrovascular reactivity, depression, end-stage renal disease, transcranial Doppler sonography |
| الوصف: | Objective To investigate the relationship between cerebrovascular reactivity (CVR) and emotional disorders in the patients undergoing continuous hemodialysis for end-stage renal disease (ESRD).Methods The clinical data of the ESRD patients undergoing continuous hemodialysis were collected.Anxiety and depression of the patients were assessed by the Hamilton anxiety scale (HAMA) and Beck depression inventory,respectively.The cerebral hemodynamic changes during the breath holding test were monitored by transcranial Doppler sonography,and the breath-holding index (BHI) was calculated.The BHI≥0.69 and BHI<0.69 indicate normal CVR and abnormal CVR,respectively.Binary Logistic regression was employed to analyze the factors affecting the depressive state of ESRD patients.Results The group with abnormal CVR exhibited higher total cholesterol level (P=0.010),low density lipoprotein level (P=0.006),and incidence of depression (P=0.012) than the group with normal CVR.Compared with the non-depression group,the depression group displayed prolonged disease course (P=0.039),reduced body mass index (P=0.048),elevated HAMA score (P=0.001),increased incidence of anxiety (P<0.001),decreased BHI (P=0.015),and increased incidence of abnormal CVR (P=0.012).Binary Logistic regression analysis indicated anxiety as a contributing factor (OR=22.915,95%CI=2.653-197.956,P=0.004) and abnormal CVR as a risk factor (OR=0.074,95%CI=0.008-0.730,P=0.026) for depression.Conclusion Impaired CVR could pose a risk for depression in the patients with ESRD. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.3881/j.issn.1000-503X.15891Test; https://pubmed.ncbi.nlm.nih.gov/38864299Test |
| DOI: | 10.3881/j.issn.1000-503X.15891 |
| الإتاحة: | https://doi.org/10.3881/j.issn.1000-503X.15891Test https://pubmed.ncbi.nlm.nih.gov/38864299Test |
| رقم الانضمام: | edsbas.BB9A1399 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3881/j.issn.1000-503X.15891 |
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