دورية أكاديمية
Prevalence of concomitant rheumatologic diseases and autoantibody specificities among racial and ethnic groups in SLE patients
| العنوان: | Prevalence of concomitant rheumatologic diseases and autoantibody specificities among racial and ethnic groups in SLE patients |
|---|---|
| المؤلفون: | Denvir, Brendan, Carlucci, Philip M., Corbitt, Kelly, Buyon, Jill P., Belmont, H. Michael, Gold, Heather T., Salmon, Jane E., Askanase, Anca, Bathon, Joan M., Geraldino-Pardilla, Laura, Ali, Yousaf, Ginzler, Ellen M., Putterman, Chaim, Gordon, Caroline, Barbour, Kamil E., Helmick, Charles G., Parton, Hilary, Izmirly, Peter M. |
| المصدر: | Frontiers in Epidemiology ; 4 |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Sjögren's disease, antiphospholipid syndrome, autoantibodies, fibromyalgia, systemic lupus erythematosus |
| الوصف: | Objective: Leveraging the Manhattan Lupus Surveillance Program (MLSP), a population-based registry of cases of systemic lupus erythematosus (SLE) and related diseases, we investigated the proportion of SLE with concomitant rheumatic diseases, including Sjögren's disease (SjD), antiphospholipid syndrome (APLS), and fibromyalgia (FM), as well as the prevalence of autoantibodies in SLE by sex and race/ethnicity. Methods: Prevalent SLE cases fulfilled one of three sets of classification criteria. Additional rheumatic diseases were defined using modified criteria based on data available in the MLSP: SjD (anti-SSA/Ro positive and evidence of keratoconjunctivitis sicca and/or xerostomia), APLS (antiphospholipid antibody positive and evidence of a blood clot), and FM (diagnosis in the chart). Results: 1,342 patients fulfilled SLE classification criteria. Of these, SjD was identified in 147 (11.0%, 95% CI 9.2-12.7%) patients with women and non-Latino Asian patients being the most highly represented. APLS was diagnosed in 119 (8.9%, 95% CI 7.3-10.5%) patients with the highest frequency in Latino patients. FM was present in 120 (8.9%, 95% CI 7.3-10.5) patients with non-Latino White and Latino patients having the highest frequency. Anti-dsDNA antibodies were most prevalent in non-Latino Asian, Black, and Latino patients while anti-Sm antibodies showed the highest proportion in non-Latino Black and Asian patients. Anti-SSA/Ro and anti-SSB/La antibodies were most prevalent in non-Latino Asian patients and least prevalent in non-Latino White patients. Men were more likely to be anti-Sm positive. Conclusion: Data from the MLSP revealed differences among patients classified as SLE in the prevalence of concomitant rheumatic diseases and autoantibody profiles by sex and race/ethnicity underscoring comorbidities associated with SLE. ; VoR ; SUNY Downstate ; Rheumatology ; N/A |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| تدمد: | 2674-1199 |
| العلاقة: | https://www.frontiersin.org/articles/10.3389/fepid.2024.1334859/fullTest; Denvir B, Carlucci PM, Corbitt K, Buyon JP, Belmont HM, Gold HT, Salmon JE, Askanase A, Bathon JM, Geraldino-Pardilla L, Ali Y, Ginzler EM, Putterman C, Gordon C, Barbour KE, Helmick CG, Parton H, Izmirly PM. Prevalence of concomitant rheumatologic diseases and autoantibody specificities among racial and ethnic groups in SLE patients. Front Epidemiol. 2024 Mar 6;4:1334859. doi:10.3389/fepid.2024.1334859. PMID: 38516120; PMCID: PMC10956350.; http://hdl.handle.net/20.500.12648/14814Test |
| DOI: | 10.3389/fepid.2024.1334859 |
| الإتاحة: | https://doi.org/20.500.12648/14814Test https://doi.org/10.3389/fepid.2024.1334859Test https://hdl.handle.net/20.500.12648/14814Test |
| حقوق: | https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.BAA72397 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 26741199 |
|---|---|
| DOI: | 10.3389/fepid.2024.1334859 |