دورية أكاديمية
Endothelial microRNAs and long noncoding RNAs in cardiovascular ageing
| العنوان: | Endothelial microRNAs and long noncoding RNAs in cardiovascular ageing |
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| المؤلفون: | Bink, Diewertje I., Pauli, Jessica, Maegdefessel, Lars, Boon, Reinier A. |
| المصدر: | Bink , D I , Pauli , J , Maegdefessel , L & Boon , R A 2023 , ' Endothelial microRNAs and long noncoding RNAs in cardiovascular ageing ' , Atherosclerosis , vol. 374 , pp. 99-106 . https://doi.org/10.1016/j.atherosclerosis.2023.03.019Test |
| سنة النشر: | 2023 |
| الوصف: | Atherosclerosis and numerous other cardiovascular diseases develop in an age-dependent manner. The endothelial cells that line the vessel walls play an important role in the development of atherosclerosis. Non-coding RNA like microRNAs and long non-coding RNAs are known to play an important role in endothelial function and are implicated in the disease progression. Here, we summarize several microRNAs and long non-coding RNAs that are known to have an altered expression with endothelial aging and discuss their role in endothelial cell function and senescence. These processes contribute to aging-induced atherosclerosis development and by targeting the non-coding RNAs controlling endothelial cell function and senescence, atherosclerosis can potentially be attenuated. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://research.vumc.nl/en/publications/7e5bad30-a8ec-428d-96c1-c78ddf6547f5Test |
| DOI: | 10.1016/j.atherosclerosis.2023.03.019 |
| الإتاحة: | https://doi.org/10.1016/j.atherosclerosis.2023.03.019Test https://research.vumc.nl/en/publications/7e5bad30-a8ec-428d-96c1-c78ddf6547f5Test http://www.scopus.com/inward/record.url?scp=85152248715&partnerID=8YFLogxKTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.BA4F12E2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.atherosclerosis.2023.03.019 |
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