دورية أكاديمية
Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
| العنوان: | Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study |
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| المؤلفون: | Joel Reuben Abel, Lorenzo Andreani, D’arienzo Antonio, Vittorio Aprile, Riccardo Balestri, Giacomo Benettini, Stefano Berrettini, Luca Bruschini, Massimo Chiarugi, Federico Coccolini, Simone Colangeli, Camilla Cremonini, Lodovica Cristofani Mencacci, Iacopo Dallan, Silvia De Santi, Gregorio Di Franco, Lorena Di Girolami, Giacomo Fiacchini, Niccolò Furbetta, Stylianos Korasidis, Marco Lucchi, Andrea Morandi, Luca Morelli, Serena Musetti, Carlo Maria Neri, Matteo Palmeri, Miriana Picariello, Francesco Porcelli, Marco Puccini, Nicolo’ Roffi, Erica Statuti, Dario Tartaglia, Alberto Tonelli, Matteo Vianini |
| المساهمون: | Reuben Abel, Joel, Andreani, Lorenzo, Antonio, D’Arienzo, Aprile, Vittorio, Balestri, Riccardo, Benettini, Giacomo, Berrettini, Stefano, Bruschini, Luca, Chiarugi, Massimo, Coccolini, Federico, Colangeli, Simone, Cremonini, Camilla, Cristofani Mencacci, Lodovica, Dallan, Iacopo, De Santi, Silvia, DI FRANCO, Gregorio, Di Girolami, Lorena, Fiacchini, Giacomo, Furbetta, Niccolò, Korasidis, Styliano, Lucchi, Marco, Morandi, Andrea, Morelli, Luca, Musetti, Serena, Maria Neri, Carlo, Palmeri, Matteo, Picariello, Miriana, Porcelli, Francesco, Puccini, Marco, Roffi, Nicolo’, Statuti, Erica, Tartaglia, Dario, Tonelli, Alberto, Vianini, Matteo |
| سنة النشر: | 2021 |
| المجموعة: | ARPI - Archivio della Ricerca dell'Università di Pisa |
| مصطلحات موضوعية: | COVID-19, delay, SARS-CoV-2, surgery, timing |
| الوصف: | Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0–2weeks, 3–4weeks and 5–6weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3–4.8), 3.9 (2.6–5.1) and 3.6 (2.0–5.2), respectively). Surgery performed ≥7weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9–2.1)). After a ≥7week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2–8.7) vs. 2.4% (95%CI 1.4–3.4) vs. 1.3% (95%CI 0.6–2.0), respectively). Where possible, surgery should be delayed for at least 7weeks following SARS-CoV-2 infection. Patients with ongoing symptoms ≥7weeks from diagnosis may benefit from further delay. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/33690889; info:eu-repo/semantics/altIdentifier/wos/WOS:000626707000001; volume:76; issue:6; firstpage:748; lastpage:758; numberofpages:11; journal:ANAESTHESIA; https://hdl.handle.net/11568/1101516Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85102236123 |
| DOI: | 10.1111/anae.15458 |
| الإتاحة: | https://doi.org/10.1111/anae.15458Test https://hdl.handle.net/11568/1101516Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.BA05D4D7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/anae.15458 |
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