دورية أكاديمية
Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment
| العنوان: | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
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| المؤلفون: | Dimitriadis, Stavros, Castells Sánchez, Alba, Roig Coll, Francesca, Dacosta Aguayo, Rosalía, Lamonja Vicente, Noemí, Toran Monserrat, Pere, García Molina, Alberto, Monte Rubio, Gemma, Stillman, Chelsea, Perera Lluna, Alexandre, Mataro Serrat, Maria |
| المساهمون: | Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial, Universitat Politècnica de Catalunya. TecSalut - Grup de Recerca en Tecnologies de la Salut |
| بيانات النشر: | Springer Nature |
| سنة النشر: | 2023 |
| المجموعة: | Universitat Politècnica de Catalunya, BarcelonaTech: UPCommons - Global access to UPC knowledge |
| مصطلحات موضوعية: | Àrees temàtiques de la UPC::Informàtica, Àrees temàtiques de la UPC::Ciències de la salut::Medicina::Neurologia, Exercise therapy, Neurosciences, Computational neuroscience, Middle aged persons, Aerobic exercise, Computerized cognitive training, Combined training, MRI, Resting-state functional connectivity, Default mode network, Multiplexity, Exercici terapèutic, Neurociències, Neurociència computacional, Persones de mitjana edat |
| الوصف: | Lifestyle interventions have positive neuroprotective effects in aging. However, there are still open questions about how changes in resting-state functional connectivity (rsFC) contribute to cognitive improvements. The Projecte Moviment is a 12-week randomized controlled trial of a multimodal data acquisition protocol that investigated the effects of aerobic exercise (AE), computerized cognitive training (CCT), and their combination (COMB). An initial list of 109 participants was recruited from which a total of 82 participants (62% female; age¿=¿58.38¿±¿5.47) finished the intervention with a level of adherence¿>¿80%. Only in the COMB group, we revealed an extended network of 33 connections that involved an increased and decreased rsFC within and between the aDMN/pDMN and a reduced rsFC between the bilateral supplementary motor areas and the right thalamus. No global and especially local rsFC changes due to any intervention mediated the cognitive benefits detected in the AE and COMB groups. Projecte Moviment provides evidence of the clinical relevance of lifestyle interventions and the potential benefits when combining them. ; Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Projecte Moviment is a project funded by the Spanish Ministry of Economy and Competitiveness under two grants: Neuroplasticity in the adulthood: physical exercise and cognitive training (PSI2013-47724-P) and Integrative omics study on the neurobiological effects of physical activity and cognitive stimulation (PSI2016-77475-R). It has also been rewarded with three pre-doctoral fellowships (FPU014/01460, FI-2016, and FI-2018). It was supported by the ICREA Academia Program to MM. ; SID is supported by a Beatriu de Pinós fellowship (2020 BP 00116). This work was supported by the Spanish Ministry of Economy and Competitiveness (www. mineco.gob.es) PID2021-122952OB-I00, Networking Biomedical Research Centre in the subject area of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), initiatives of ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2509-2723 |
| العلاقة: | https://link.springer.com/article/10.1007/s11357-023-00946-8Test; info:eu-repo/grantAgreement/MINECO//PSI2013-47724-P/ES/NEUROPLASTICIDAD EN LA EDAD ADULTA: EJERCICIO FISICO Y ENTRENAMIENTO COGNITIVO/; info:eu-repo/grantAgreement/EC/H2020/780262/EU/Social media platform dedicated to rare diseases, using collective intelligence for the generation of awareness and advanced knowledge on this large group of diseases./SHARE4RARE; Dimitriadis, S. [et al.]. Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment. "GeroScience", 23 Octubre 2023, vol. 46, p. 573-596.; http://hdl.handle.net/2117/396425Test |
| DOI: | 10.1007/s11357-023-00946-8 |
| الإتاحة: | https://doi.org/10.1007/s11357-023-00946-8Test http://hdl.handle.net/2117/396425Test |
| حقوق: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0Test/ ; Open Access |
| رقم الانضمام: | edsbas.B9F8F232 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 25092723 |
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| DOI: | 10.1007/s11357-023-00946-8 |