التفاصيل البيبلوغرافية
| العنوان: |
Pediatric Parapneumonic Effusion/Pleural Empyema in Japan ; A Nationwide Survey |
| المؤلفون: |
Hoshino, Tadashi, Nishima, Daisuke, Enseki, Mayumi, Umehara, Naoki, Fukasawa, Chie, Ishiwada, Naruhiko |
| المصدر: |
Pediatric Infectious Disease Journal ; volume 41, issue 1, page 20-23 ; ISSN 0891-3668 |
| بيانات النشر: |
Ovid Technologies (Wolters Kluwer Health) |
| سنة النشر: |
2021 |
| الوصف: |
Background: Pediatric parapneumonic effusion/ pleural empyema (PPE/PE) is a severe infectious condition, and its management should be guided by local epidemiology and the patient’s medical history. This survey aimed to determine the clinical and bacteriologic features of PPE/PE in Japan. Methods: A nationwide retrospective questionnaire survey was conducted, targeting 159 pediatric specialist training medical facilities for inpatients ≤18 years of age who were admitted for PPE/PE between January 2007 and December 2016. Results: Valid responses were obtained from 122 facilities, and 96 patients were identified from 38 facilities. The median age (interquartile range) was 2.7 (0.8–7.8) years. Overall, 60 (63 %) patients were men and 49 (51%) had comorbidities. The causative bacteria were identified in 59% of patients by culture except in one case identified using PCR. Streptococcus pyogenes (16%), Staphylococcus aureus (14%) and Streptococcus pneumoniae (13%) were the major pathogens. Carbapenems were administered to 34% of patients without comorbidities. Chest tube drainage was performed in 71%, intrapleural fibrinolytic therapy in 9.4%, surgery in 25% and mechanical ventilation in 29% of the patients. Five patients (5.2%) had complications and one (1.1%) had sequelae, but all patients (100%) survived. Conclusions: This is first report of a nationwide survey pertaining to pediatric PPE/PE in Japan. We found that the etiology showed a different trend from that reported in other countries. It is worrisome that molecular methods were rarely used for pathogenic diagnosis and carbapenems were overused. Thus, it is imperative to establish clinical guidelines for PPE/PE in Japan. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1097/inf.0000000000003353 |
| DOI: |
10.1097/INF.0000000000003353 |
| الإتاحة: |
https://doi.org/10.1097/inf.0000000000003353Test |
| رقم الانضمام: |
edsbas.B9698119 |
| قاعدة البيانات: |
BASE |
