Data_Sheet_3_A Simple Approach for Experimental Characterization and Validation of Proton Pencil Beam Profiles.PDF

التفاصيل البيبلوغرافية
العنوان: Data_Sheet_3_A Simple Approach for Experimental Characterization and Validation of Proton Pencil Beam Profiles.PDF
المؤلفون: Paulina Stasica, Jakub Baran, Carlos Granja, Nils Krah, Grzegorz Korcyl, Cristina Oancea, Monika Pawlik-Niedźwiecka, Szymon Niedźwiecki, Marzena Rydygier, Angelo Schiavi, Antoni Rucinski, Jan Gajewski
سنة النشر: 2020
مصطلحات موضوعية: Biophysics, Astrophysics, Applied Physics, Computational Physics, Condensed Matter Physics, Particle Physics, Plasma Physics, Solar System, Solar Physics, Planets and Exoplanets, Classical and Physical Optics, Photonics, Optoelectronics and Optical Communications, Cloud Physics, Tropospheric and Stratospheric Physics, High Energy Astrophysics, Cosmic Rays, Mesospheric, Ionospheric and Magnetospheric Physics, Space and Solar Physics, Mathematical Physics not elsewhere classified, Physical Chemistry of Materials, Physical Chemistry not elsewhere classified, Classical Physics not elsewhere classified, Condensed Matter Physics not elsewhere classified, Quantum Physics not elsewhere classified, proton therapy, dose, semiconductor pixel detector, Timepix detector
الوصف: A precise characterization of therapeutic proton pencil beams is essential for the commissioning of any treatment planning system (TPS). The dose profile characterization includes measurement of the beam lateral dose profile in the beam core and far from the beam core, in the so called low-dose envelope, and requires a sophisticated detection system with a few orders of magnitude dynamic range. We propose the use of a single-quantum-sensitive MiniPix Timepix detector, along with an in-house-designed holder to perform measurements of the pencil beam dose profile in air and in water. We validated the manufacturer calibration of the MiniPix Timepix detector in proton beams of various energies and compared the deposited energy spectra to Monte Carlo (MC) simulations. The precision of the lateral dose profile measurements has been systematically validated against Krakow proton facility commissioning data and dose profile simulations performed with MC codes Gate/Geant4 and Fred. We obtained an excellent agreement between MiniPix Timepix measurements and simulations demonstrating the feasibility of the system for a simple characterization and validation of proton pencil beams. The proposed approach can be implemented at any proton therapy facility to acquire experimental data needed to commission and validate analytical and MC-based TPS.
نوع الوثيقة: dataset
اللغة: unknown
العلاقة: https://doi.org/10.3389/fphy.2020.00346.s003Test
DOI: 10.3389/fphy.2020.00346.s003
الإتاحة: https://doi.org/10.3389/fphy.2020.00346.s003Test
حقوق: undefined
رقم الانضمام: edsbas.B937F2B
قاعدة البيانات: BASE