دورية أكاديمية
An Assessment of Anticancer Activity (MCF-7) and Free Radicals Scavenging Potential of Ferula Asafoetida Synthesized AgNPs through In Vitro Analyses
| العنوان: | An Assessment of Anticancer Activity (MCF-7) and Free Radicals Scavenging Potential of Ferula Asafoetida Synthesized AgNPs through In Vitro Analyses |
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| المؤلفون: | Nguyen Chi Thanh, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Deepika Joshi, G. K. Jhanani, Adisu Haile |
| المصدر: | Journal of Nanomaterials, Vol 2022 (2022) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Technology (General), T1-995 |
| الوصف: | Nanomaterials are increasingly being used in pharmaceutical industry to treat a variety of disorders and diseases. Hence, the aim of this research was to evaluate their antioxidant and anticancer activity of presynthesized and characterized plant-based AgNPs against ferric, DPPH, H2O2, and ABTS free radicals and MCF-7 cell line. Interestingly, the antioxidants assay results revealed that the increased concentration (100 μg mL-1) of AgNPs has remarkable antioxidant ability on ferric (78.20%), DPPH (89.61%), H2O2 (82.34%), and ABTS (67.95%) free radicals. These scavenging activities were almost close to the free radicals scavenging ability of vitamin C (ascorbic acid). Similarly, test AgNPs showed considerable cytotoxicity (83.15%) against MCF-7 cell line, and it was partially comparable with the cytotoxicity activity (91.35%) of positive control (Doxorubicin). These findings indicate that plant-mediated AgNPs have significant antioxidant and anticancer activity, and thus may be considered for biomedical applications pending the results of some in vivo experiments. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1687-4129 |
| العلاقة: | http://dx.doi.org/10.1155/2022/6095005Test; https://doaj.org/toc/1687-4129Test; https://doaj.org/article/ad82890d4f1f4eba886ea823132bf87eTest |
| DOI: | 10.1155/2022/6095005 |
| الإتاحة: | https://doi.org/10.1155/2022/6095005Test https://doaj.org/article/ad82890d4f1f4eba886ea823132bf87eTest |
| رقم الانضمام: | edsbas.B88715A0 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16874129 |
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| DOI: | 10.1155/2022/6095005 |