دورية أكاديمية
Tissue alkalosis in cold-ischemia time
| العنوان: | Tissue alkalosis in cold-ischemia time |
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| المؤلفون: | Denninghoff, V., Olivieri, E. H. R., Fresno, C., Uceda, A., Mota, L., Suenaga, A. P., Carraro, D. M., Martins, V. R., Avagnina, A., Soares, F. A., Campos, A. H. J. Fróes Marques |
| المصدر: | Scientific Reports ; volume 7, issue 1 ; ISSN 2045-2322 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Multidisciplinary |
| الوصف: | The control of pre-analytical-factors in human biospecimens collected for health research is currently required. Only two previous reports using post-mortem brain samples have tried to address the impact of cold-ischemia on tissue pH. Here we report pH variations according to time (third-order polynomial model) in mice for liver, kidney and lung samples. Tissue alkalosis in cold-ischemia time may be an underlying mechanism of gene expression changes. Therefore, tissue-pH regulation after organ removal may minimize biological stress in human tissue samples. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1038/s41598-017-11284-z |
| الإتاحة: | https://doi.org/10.1038/s41598-017-11284-zTest https://www.nature.com/articles/s41598-017-11284-z.pdfTest https://www.nature.com/articles/s41598-017-11284-zTest |
| حقوق: | https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: | edsbas.B3179139 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41598-017-11284-z |
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