دورية أكاديمية
Relationship of device measured physical activity type and posture with cardiometabolic health markers:pooled dose–response associations from the Prospective Physical Activity, Sitting and Sleep Consortium
| العنوان: | Relationship of device measured physical activity type and posture with cardiometabolic health markers:pooled dose–response associations from the Prospective Physical Activity, Sitting and Sleep Consortium |
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| المؤلفون: | Ahmadi, Matthew N., Blodgett, Joanna M., Atkin, Andrew J., Chan, Hsiu Wen, del Pozo Cruz, Borja, Suorsa, Kristin, Bakker, Esmee A., Pulsford, Richard M., Mielke, Gregore I., Johansson, Peter J., Hettiarachchi, Pasan, Thijssen, Dick H.J., Stenholm, Sari, Mishra, Gita D., Teixeira-Pinot, Armando, Rangul, Vegar, Sherar, Lauren B., Ekelund, Ulf, Hughes, Alun D., Lee, I. Min, Holtermann, Andreas, Koster, Annemarie, Hamer, Mark, Stamatakis, Emmanuel |
| المصدر: | Ahmadi , M N , Blodgett , J M , Atkin , A J , Chan , H W , del Pozo Cruz , B , Suorsa , K , Bakker , E A , Pulsford , R M , Mielke , G I , Johansson , P J , Hettiarachchi , P , Thijssen , D H J , Stenholm , S , Mishra , G D , Teixeira-Pinot , A , Rangul , V , Sherar , L B , Ekelund , U , Hughes , A D , Lee , I M , ProPASS collaboration , .... |
| سنة النشر: | 2024 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| مصطلحات موضوعية: | Cardiometabolic health, Individual participant meta-analysis, Physical activity type, Posture, Running, Sitting, Stair climbing, Standing, Walking, Wearables, Waist Circumference/physiology, Prospective Studies, Cardiovascular Diseases/prevention & control, Humans, Middle Aged, Male, Posture/physiology, Sleep/physiology, Standing Position, Walking/physiology, Female, Adult, Biomarkers/blood, Stair Climbing/physiology, Body Mass Index, Cross-Sectional Studies, Exercise/physiology, Sitting Position, Cholesterol, HDL/blood |
| الوصف: | AIMS/HYPOTHESIS: The aim of this study was to examine the dose-response associations of device-measured physical activity types and postures (sitting and standing time) with cardiometabolic health. METHODS: We conducted an individual participant harmonised meta-analysis of 12,095 adults (mean ± SD age 54.5±9.6 years; female participants 54.8%) from six cohorts with thigh-worn accelerometry data from the Prospective Physical Activity, Sitting and Sleep (ProPASS) Consortium. Associations of daily walking, stair climbing, running, standing and sitting time with a composite cardiometabolic health score (based on standardised z scores) and individual cardiometabolic markers (BMI, waist circumference, triglycerides, HDL-cholesterol, HbA 1c and total cholesterol) were examined cross-sectionally using generalised linear modelling and cubic splines. RESULTS: We observed more favourable composite cardiometabolic health (i.e. z score <0) with approximately 64 min/day walking (z score [95% CI] -0.14 [-0.25, -0.02]) and 5 min/day stair climbing (-0.14 [-0.24, -0.03]). We observed an equivalent magnitude of association at 2.6 h/day standing. Any amount of running was associated with better composite cardiometabolic health. We did not observe an upper limit to the magnitude of the dose-response associations for any activity type or standing. There was an inverse dose-response association between sitting time and composite cardiometabolic health that became markedly less favourable when daily durations exceeded 12.1 h/day. Associations for sitting time were no longer significant after excluding participants with prevalent CVD or medication use. The dose-response pattern was generally consistent between activity and posture types and individual cardiometabolic health markers. CONCLUSIONS/INTERPRETATION: In this first activity type-specific analysis of device-based physical activity, ~64 min/day of walking and ~5.0 min/day of stair climbing were associated with a favourable cardiometabolic risk profile. The deleterious ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://portal.findresearcher.sdu.dk/da/publications/02684ac3-e426-4cc8-8863-fa9b72c57a83Test |
| DOI: | 10.1007/s00125-024-06090-y |
| الإتاحة: | https://doi.org/10.1007/s00125-024-06090-yTest https://portal.findresearcher.sdu.dk/da/publications/02684ac3-e426-4cc8-8863-fa9b72c57a83Test https://findresearcher.sdu.dk/ws/files/259713223/s00125-024-06090-y.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B1ECB0B8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00125-024-06090-y |
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